Table 1. Baseline Characteristics of Patients With Pediatric Ventilator-Associated Conditions (VAC) in the Cardiac, Pediatric, and Neonatal Intensive Care Units and Their Matched Controls CICU (N=86)
PICU (N=140) VAC (N=43) AVAC Characteristic
Age (mo) or gestational age (weeks, NICU), median (IQR) Gender (female) no. (%)
NICU birth weight, g, median (IQR) 5-min APGAR score (NICU), median (IQR)
Chronic comorbidities Prematurity, no. (%)
Cardiac condition, no. (%)a Pulmonary condition, no. (%) Neurologic condition, no. (%) Renal condition, no. (%) GI condition, no. (%)
Trach/vent dependent, no. (%) Congenital anomaly, no. (%)b Immunosuppressed, no. (%)
Acute conditions ± 2 d of VAC/index date Recent surgical procedures, no. (%)
New antimicrobial use ± 2 d of VAC/index date, no. (%) Respiratory diagnostic testing ±2 d of VAC/index date, no. (%)
7 (16)
41 (95) 5 (12) 4 (9) 2 (5)
5 (12) 3 (7)
9 (21) 3 (7)
18 (42) 25 (58) 3 (7)
4 (16)
24 (96) 3 (12) 2 (8) 0 (0)
4 (16) 1 (4)
6 (24) 1 (4)
11 (44) … …
7 (16)
40 (93) 8 (19) 6 (14) 0 (0)
12 (28) 2 (5)
7 (16) 0 (0)
11 (26) 11 (26) 1 (2)
12 (17) 15 (21) 15 (21) 12 (17) 6 (9)
18 (25) 4 (6)
12 (17) 20 (29)
10 (14) 36 (51) 7 (10)
8 (22) 9 (25) 6 (17) 5 (14) 3 (8)
10 (28) 1 (3)
7 (19) 11 ((31)
6 (17) … …
9 (13)
11 (16) 17 (24) 23 (33) 2 (3)
16 (23) 13 (19) 21 (30) 8 (12)
15 (21) 25 (36) 8 (11)
All 0 (0–9) 20 (46)
(N=25) 0 (0–9)
12 (48) All 18 (42) All
Control (N=43)
VAC (N=70) AVAC (N=36) 16 (44) All
0 (0–6) 49 (12–157) 33 (7–110) 53 (11–134) 36 (51)
30 (43) All
27 (25–32) 35 (44)
Control (N=70)
VAC (N=79) AVAC (N=18)
27 (25–35) 9 (50)
8 (6–8) All
27 (25–34) 36 (45)
930 (705–2,000) 920 (710–2,152) 980 (720– 1,750) 7(5–8)
7 (6–8)
62 (78) 43 (53) 33 (42) 9 (11) 6 (8)
20 (25) 1 (1) 6 (8) 1 (1)
24 (30) 18 (28) 5 (6)
NOTE: CICU, cardiac intensive care unit; PICU, pediatric intensive care unit; NICU, neonatal intensive care unit; VAC, ventilator-associated condition; AVAC, VAC with antimicrobial use. aStructural heart disease, valvular disease, septal defect, arrhythmia or cardiomyopathy. bCongenital anomaly or malformation.
14 (78) 9 (50)
10 (56) 4 (22) 3 (17) 3 (17) 0 (0) 1 (6) 1 (6)
8 (44)
… …
60 (76) 32 (40) 27 (34) 12 (15) 6 (8)
23 (29) 6 (8) 5 (6)
0 (0%)
12 (15) 8 (20) 1 (1)
NICU (N=158)
Control (N=79)
34
Manjiree V. Karandikar et al
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