getting consumed, getting lost or not getting absorbed into the brain as efficiently with the E4 gene," Dr. Yassine stated. The 2-gram dose of omega-3s used in this trial doubles the typical 1-gram dose used in prior major clinical trials on omega-3s for AD prevention. Dr. Yassine warns that using a 1-gram omega-3 supplement

correlates to a less than 10% increase in omega-3s in the brain, a dose that he says, "may not be considered meaningful" in the fight against Alzheimer's disease progression. The research team concluded that even higher doses of

omega-3 fatty acids may be required to slow signs of declining brain health in carriers of the APOE4 gene. The USC research team's results were published in July 2020

in the journal EBioMedicine. Dr. Yassine has obtained additional funding for a larger, longer trial on whether high doses of omega- 3s can slow cognitive decline in carriers of the APOE4 gene. The two-year study, to be conducted on 320 participants,

has a near-term goal to establish proof-of-concept that the drug is getting into the brain and positively affecting the biomarkers of disease. Researchers ultimately hope to identify and develop therapies for preventing AD.

Omega-3s Provide 60 Known Health Benefits The consumption of fat is a frequent topic of food wars among health-conscious individuals. The idea of healthy fats versus unhealthy fats is no longer considered controversial, and omega-3 fatty acids are arguably the most well-known of the "good" fats. If you prefer to obtain healthy fats from food sources rather

than supplements, fish such as mackerel, sardines and salmon are among the best sources of omega-3 fats. Besides the brain health benefits, eating fish and foods high in vitamin D and

omega-3s may help you prevent heart attacks and stave off can- cer.

The 60 known health benefits of omega-3 fatty acids are:

1. There is strong evidence that omega-3 fatty acids have a beneficial effect in bipolar disorder.

2. Omega-3 fatty acid supplementation is associated with re- duced mania and depression in juvenile bipolar disorder.

3. Clinical studies have reported that oral fish oil supplemen- tation has beneficial effects in rheumatoid arthritis and among some asthmatics.

4. Fish oil improves tubular dysfunction, lipid profiles and oxidative stress in patients with IgA nephropathy.

5. Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients.

6. Omega 3 fatty acids improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity.

7. Omega-3 in modest doses reduces cardiac deaths, and in high doses reduces nonfatal cardiovascular events.

8. Dietary supplementation with omega-3 fatty acids reduces the incidence of sudden cardiac death in patients with myo- cardial infarction.

Dixon & Associates Therapy Services

We look at each patient as a unique individual, not a diagnosis. Personal attention is what our success is based on,

and our whole company is set up to make everyone’s experience with therapy a positive one.

Lori Dixon, OT/L Our Specialties:

Myofascial Release • Chronic Pain • Neck & Back Pain CranioSacral Therapy • TMJ Dysfunction

Women’s Health Issues • Hand Injuries • Orthopaedic Injuries Functional Capacity Evaluations (FCEs) • Worker’s Compensation

We file medical insurance and Medicare • BlueCross/Blue Shield Provider 336.889.5676

204 Gatewood Avenue • High Point, NC 27262

NOVEMBER 2020 23

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