have also been shown nearly equipotent to Prozac (fluoxetine) as a treatment for depression. According to a study published in the Progress in Neuropsychopharmacol- ogy and Biological Psychiatry in 2007, 15 mg of Crocus sativus petals were as effec- tive as 10 mg of Prozac in treating mild to moderate depression, putting 25% of the participants into full remission. Another depression study published 2004 showed that saffron, at 30 mg a day, was as effec- tive as the drug imipramine, at 100 mg a day, in the treatment of mild to moderate depression. Other experimentally confirmed thera- peutic applications of Saffron include:
Anxiety Disorders Asthenozoospermia (low sperm) Cardiac Hypertrophy Chemotherapy-Induced Liver Toxicity Colorectal Cancer Diabetic Neuropathy
Dysmenorrhea (irregular menstrual cycles)
Erectile Dysfunction Hypertension Inflammation Liver Cancer Middle Cerebral Artery Occlusion Multiple Sclerosis
Opiate Addiction/Withdrawal Pancreatic Cancer Psoriasis Respiratory Disease Wound Healing
Saffron has been shown to modulate
over 50 biological pathways, including but not limited to the following pharmaco- logical actions:
Anti-anxiety
Anti-inflammatory Anticarcinogenic Antidepressive Antimutagenic Antioxidant Antiproliferative Aphrodisiac Apoptotic Bronchodilator
Calcium Channel Blocker Cardioprotective Chemopreventive Chremotherapeutic Cyclooxygenase inhibitor Excitatory Amino Acid Agonist Hypnotics and Sedatives Hypotensive Neuroprotective
Prostaglandin Antagonists Tumor Necrosis Factor Alpha Inhibitor
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A note of caution is due with saffron,
as any plant with such a great many modes of action and high biological activity at exceedingly low quantities, should be used with caution. In very small amounts, an herb like saffron may nudge a system into balance, or in a direction that the user may experience as a positive shift -- for example, as occurs when saffron is used in a dish as a spice, or consumed as a tea. However, in higher "pharmacological dos- ages," especially when mixed with over- the-counter and prescribed drugs, there is a risk of doing serious harm. Therefore please be careful, and consult a medical herbalist and/or physician whenever pos- sible before using larger than culinary doses of saffron.
Written by Sayer Ji, founder of GreenMed Info. © August, 2018 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMed- Info? Sign up for the newsletter here
http://www.greenmedinfo.com/ greenmed/newsletter.
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