INTERVIEWS WITH N. SPOONER & J. RUDGE
and they’ve never been able to before and maybe now you can help them. Don’t use it for everything, but use it where it’s appropriate and where it’s going to give you good quality data.
JR: For me it would be to learn as much as you can – go to conferences, read journals. It’s a new technology – yes, it’s been around for a while but back in the 1960s those blood spots were essentially analysed by semi-quantitative methods. There are a lot more challenges now as we’re really trying to tighten up the quantitation. So don’t give up!
Click on video to play 39
Q
Where do you see the field in the next 5-10 years?
NS: Hopefully in 5-10 years we’ll see microsampling being a standard technique in areas where it provides a real benefit over standard sampling – hopefully in discovery and development toxicology studies and PK studies it will be standard practice, and hopefully in paediatric clinical studies and areas where we need to collect extra samples in remote areas or at-home sampling it will be standard practice.
JR: In the next 5-10 years, because of the massive increase in computing power and instrument sensitivity and specificity, I see a whole raft of biomarkers coming out for various clinical reasons, so there’ll be a whole pile of new tests compatibile with microsampling that’s going to be clinically relevant and clinically available. Perhaps in the next 20 years I hope that with just one drop of blood we’ll be able to analyze the genome, phenome and metabolome, and then detect and personalize the treatment of a disease based on one blood spot.
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