ASK THE EXPERT
“ There will be continued advancements in the specificity of microsampling techniques. ”
be continued growth in this area, but microsampling techniques will be complimentary and in some cases displace existing accepted methodologies.
Q 24 How do you see microsampling techniques evolving over the next 5–10 years?
Advancements to provide real time patient diagnostics are becoming closer through the innovations in microsampling. The development of MS-based platforms with simplified user interfaces has the potential to make bedside therapeutics more common in the near future. The advancements in direct MS analysis using devices such as DESI and DART have shown the potential for accurate and rapid assessments with minimal sample. Microsampling will continue to play an important role in the advancement of direct analysis.
There will be continued advancements in the specificity of microsampling techniques.
Microsampling devices containing antibodies for highly specific assays are within the foreseeable future. Evolution of microsampling with biosensors has the potential to allow rapid patient assessment in under developed countries that do not have access to advanced laboratory techniques.
To learn more about solid phase microextraction for use in bioanalytical assays, please visit
http://www.sigmaaldrich.com/biospme
About the Expert
Craig Aurand is the Innovation Manager for the Advanced Analytical division of MilliporeSigma (Bellefonte, PA, USA). Craig’s primary role is identification and development of innovative analytical techniques for life science applications. He is responsible for the development of innovative chromatographic and sample preparation devices for life science applications, and has published numerous presentations and publications focusing on novel chromatographic separations and sample preparation techniques. Craig has more than 15 years experience in product and application
development with emphasis in liquid chromatography/mass spectrometry techniques. His most recent research has focused on the field of microsampling techniques in bioanalysis.
www.bioanalysis-zone.com
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