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Life Sciences


environment, enabling quick entry to market for innovations and access to anonymised patient data and patients for clinical trials. Investors have the opportunity to invest in world-leading research with access to new fiscal measures to reduce costs and support risk taking. Researchers can access cutting-edge facilities,


real life data and an integrated system for bio medicine. Clinicians play an active role in innovation and research, and are better able to improve patient outcomes. Patients, meanwhile, are empowered with more choice and as a result have better access to more effective treatments. In the LSO we support overseas investment


into the UK from the earliest R&D collaborations through to clinical trials, commercial operations and partnerships. We support and promote trade opportunities alongside that of investment and recognise the need to support every component of the pathway. From bench to bedside, we are making it easier to discover, develop and deliver healthcare innovation in the UK. Businesses benefit from the opportunity to use the


UK as a launch pad to other international markets, whether in Europe or beyond. The UK’s excellent reputation in research, clinical development, health regulation, and health economics combined with UKTI’s own global connectivity mean that the UK can help businesses maximise their export and investment potential. Over my 25 years in the discovery of novel


treatments for diseases of the nervous system I have seen many changes and the UK now operates in an extremely competitive global environment. We can no longer take for granted that the UK is considered the world leader in cutting-edge clinical trials, we need to keep proving that point.


DR MARK TREHERNE


Chief Executive, UKTI Life Sciences Organisation (LSO) August 2012 - Present Mark is a research scientist with a PhD in Pharmacology from Cambridge University and has over


25 years’ industrial experience in the discovery of novel treatments for diseases of the nervous system. Formerly at Pfizer in Sandwich, UK, and responsible for research into neurodegenerative diseases before leaving Pfizer in 1997 to set up Cambridge Drug Discovery (CDD) as Chief Executive, which was sold to BioFocus in 2001. Mark has helped to raise funds for various early-stage biotechnology companies and has now served on the Boards of over 15 private and public biopharmaceutical companies around the world. Mark is Chief Executive of the LSO and leads a team of senior civil servants and sector specialists working together to support the Government’s Industrial Strategy and support overseas investment into the UK from the earliest R&D collaborations through to clinical trials, commercial operations and partnerships. The LSO team also offer trade support to exporting companies and companies seeking to export from the UK.


Life Sciences Organisation In the UK, partners work together to support a


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research and innovation culture that spans sectors and geographies, and supports the creation of a fully integrated life science and healthcare ecosystem that places the patient at the heart of the system. Globally, there is a growing demand for stratified medicines and companion diagnostics. With first class research and expertise, world leading data & translational infrastructure and an established value chain, the UK has a great deal to offer in this space. The UK’s focus on improving the efficiency of the


translation of scientific discoveries into innovative products and services is showcased by the work of the National Institute for Health Research (NIHR). NIHR funding for providers of NHS services undertaking clinical trials now achieves a benchmark of 70 days or less from receipt of a valid research application to recruitment of the first participant. The NIHR Clinical Research Networks are embedded in the NHS supporting the delivery of multi-centre clinical studies. 630,000 patients were recruited in 2013 into clinical research studies. This has trebled since 2010. The NIHR Office for Clinical Research Infrastructure (NOCRI) helps businesses access world-class facilities, and well-characterised and diverse patient cohorts drawn from the 60 million people who use the NHS in the UK. These are just a few illustrations of how the UK provides an unrivalled ecosystem that brings together businesses, researchers, clinicians and patients to translate discovery into clinical use. The Francis Crick Institute, due to open in


2015, is testament to our world class standing. Housing over 1,250 scientists with a mission to understand why disease develops and find new ways to treat, diagnose and prevent illnesses such as cancer, heart disease and stroke, infections, and neurodegenerative diseases it will be one of the most significant developments in UK biomedical science for a generation. A partnership between the MRC, Cancer Research UK, the Wellcome Trust, University College London, King’s College London and Imperial College London, the Institute will not only help to improve people’s lives but will also keep the UK at the forefront of innovation in medical research and importantly foster meaningful collaborations with other centres of excellence. The ecosystem is further supported by the UK


Government’s introduction of fiscal measures to stimulate innovation and growth for companies: for example the Patent Box offers a lower corporation tax of 10% on qualifying profits, and R&D tax credits for small and medium sized enterprises gives up to 33% back on spending - one of the most generous in the world - and importantly we have corporation tax falling further to 20% by 2015. It’s these types of key points and comparative


strengths of the UK life science sector that we need to keep re-affirming to deliver the UK’s long-term commitment to life sciences on a global stage.


Further information www.lifesciences.ukti.gov.uk


global-opportunity.co.uk Issue 01 | Global Opportunity Healthcare 2015 167


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