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Metabolic Complications of Long-Term Parenteral Nutrition References


1. Badia-Tahull MB, Leiva-Badosa E, Llop-Talaverón J, et al. Liver function test alterations associated with parenteral nutrition in hospitalized adult patients: incidence and risk factors. Nutr Hosp. 2012;27(4):1279-1285. doi:10 . 3305 / nh . 2012 . 27 . 4 . 5827


2. Gabe SM, Culkin A. Abnormal liver function tests in the parenteral nutrition fed patient. Frontline Gastroenterol. 2010;1(2):98-104. doi:10 . 1136 / fg . 2009 . 000521


3. Salvino R, Ghanta R, Seidner DL, Mascha E, Xu Y, Steiger E. Liver failure is uncommon in adults receiving long-term parenteral nutrition. JPEN J Parenter Enteral Nutr. 2006;30(3):202-208. doi:10 . 1177 / 0148607106030003202


4. Xu ZW, Li YS. Pathogenesis and treatment of parenteral nutrition- associated liver disease. Hepatobiliary Pancreat Dis Int. 2012;11(6):586-593. doi:10 . 1016 / s1499 - 3872(12)60229 - x


5. Ć»alikowska-Gardocka M, Niewada M, NiewiƄski G, et al. Early predictors of liver injury in patients on parenteral nutrition. Clin Nutr ESPEN. 2022;51:319-322. doi:10 . 1016 / j . clnesp . 2022 . 08 . 007


6. Nowak K. Parenteral nutrition-associated liver disease. Clin Liver Dis (Hoboken). 2020;15(2):59-62. doi:10 . 1002 / cld . 888


7. Kumpf VJ. Complications of parenteral nutrition. In: Chan, L-N ed. ASPEN Adult Nutrition Core Curriculum. 4th ed. American Society for Parenteral and Enteral Nutrition; 2025:467-486.


8. Mirtallo JM, Ayers P, Boullata J, et al. A.S.P.E.N. lipid injectable emulsion safety recommendations, part 1: background and adult considerations. Nutr Clin Pract. 2020;35(5):769-782. doi:10 . 1002 / ncp . 10496


9. Ayers P, Bobo ES, Hunt RT, Mays AA, Worthington PH, eds. Complications of parenteral nutrition. In: ASPEN Parenteral Nutrition Handbook. 3rd edition. American Society for Parenteral and Enteral Nutrition; 2020.


10. Perks P, Huynh E, Kaluza K, Boullata JI. Advances in trace element supplementation for parenteral nutrition. Nutrients. 2022;14(9):1770. doi:10 . 3390 / nu14091770


11. Baker B, Ali A, Isenring L. Recommendations for manganese supplementation to adult patients receiving long-term home parenteral nutrition: an analysis of the supporting evidence. Nutr Clin Pract. 2016;31(2):180-185. doi:10 . 1177 / 0884533615591600


12. Borum PR. Carnitine in parenteral nutrition. Gastroenterology. 2009;137(5 suppl):s129-s34. doi:10 . 1053 / j . gastro . 2009 . 08 . 016


13. Haines KL, Ohnuma T, Trujillo C, et al. Hospital change to mixed lipid emulsion from soybean oil-based lipid emulsion for parenteral nutrition in hospitalized and critically ill adults improves outcomes: a pre-post-comparative study. Crit Care. 2022;26(1):317. doi:10 . 1186 / s13054 - 022 - 04194 - 8


14. Bering J, DiBaise JK. Short bowel syndrome: complications and management. Nutr Clin Pract. 2023;38(Suppl 1):S46-S58. doi:10 . 1002 / ncp . 10978


15. Pironi L, Labate AM, Pertkiewicz M, et al. Prevalence of bone disease in patients on home parenteral nutrition. Clin Nutr. 2002;21(4):289-296. doi:10 . 1054 / clnu . 2002 . 0548


16. Hartl WH, Jauch KW, Parhofer K, Rittler P; Working Group for Developing the Guidelines for Parenteral Nutrition of the German Association for Nutritional Medicine. Complications and monitoring: guidelines on parenteral nutrition, Chapter 11. Ger Med Sci. 2009;7:Doc17. doi:10 . 3205 / 000076


17. Boulétreau PH, Bost M, Fontanges E, et al. Fluoride exposure and bone status in patients with chronic intestinal failure who are receiving home parenteral nutrition. Am J Clin Nutr. 2006;83(6):1429-1437. doi:10 . 1093 / ajcn / 83 . 6 . 1429


18. Acca M, Ragno A, Francucci CM, D’Erasmo E. Metabolic bone diseases during long-term total parenteral nutrition. J Endocrinol Invest. 2007;30(6 suppl):54-59.


19. Haderslev KV, Tjellesen L, Haderslev PH, Staun M. Assessment of the longitudinal changes in bone mineral density in patients receiving home parenteral nutrition. JPEN J Parenter Enteral Nutr. 2004;28(5):289-294. doi:10 . 1177 / 0148607104028005289


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