CHAPTER 2
BOX 2.4 Late, Noninfectious Complications Associated With Central Catheters1,5,18
Complication Description
Occlusion (thrombotic, nonthrombotic, or mechanical)
Inability to aspirate or flush the catheter
Can occur if blood or precipitates form in the catheter and proper flushing procedures are not used
Determine cause; consult with pharmacy and health care team
Catheter salvage is preferred over removal
Thrombotic: includes intraluminal clot, fibrin sleeve formation, mural thrombus, or thrombosis of a vessel
Nonthrombotic: causes of intraluminal occlusions may include drug-heparin interactions, inappropriate calcium-phosphate quantities and mixing, or lipid deposits
Mechanical: risk vs benefit assessment for repair or exchange; catheter embolism can occur with catheter rupture and may result from using too much pressure when flushing the line
Breakage Requires removal or repair as soon as possible
Until removal or repair, the catheter must be clamped between where it exits the body and the break to avoid air embolism or leakage of blood
Patients receiving home parenteral nutrition should be provided a temporary emergency repair kit for use by a home care nurse
Malposition or dislodgement
All central catheters can dislodge, moving their tip position out of central circulation
Symptoms include swelling or pain in the neck, shoulder, or chest
Order a chest x-ray if dislodgement is suspected and to confirm tip location
The catheter should not be used as a central line until it is repositioned and the tip is confirmed to be in a central location
Catheter replacement is considered if the tip is in the jugular or contralateral vein or is coiled or looped; most coiled or looped peripherally inserted central catheters are managed by interventional radiology
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