VITAMIN/MINERAL


Iron (Fe) Ferritin*


Total iron binding capacity (TIBC)* Transferrin saturation (%)* Mean corpuscular volume (MCV)* Hemoglobin (Hgb)*


Manganese (Mn) Manganese


Selenium (Se) Glutathione peroxidase


Selenium


Zinc (Zn) Zinc


LABORATORY METHOD NORMAL Serum


M: 40-300 μg/L F: 20-200 μg/L


Serum Whole blood


Whole blood


Whole blood Serum or plasma


Serum or plasma 24-hour urine


15-45% 80-95 fL


INTERPRETATION DEFICIENCY TOXICITY <12-30 μg/L


>400 μg/dL ≤15% ≤80 fL


M: <13 g/dL F: <12 g/dL


5-15 μg/L 63-160 μg/L


80-120 μg/dL 0.2-1.3 mg/d


<10.5 U/mL <40 μg/L


<30 μg/dL


M: >300 μg/L F: >200 μg/L


Ferritin may be falsely increased during inflammation.


Non-anemia = decreased transferrin; elevat- ed free erythrocyte protoporphyrin (>70 μg/ dL erythrocyte).


Iron deficiency anemia = decreased MCV and Hgb.


*Usually evaluated together.


Mn in whole blood is the best monitor available at this time.


May be falsely decreased during inflammation. >400 μg/L


Serum/plasma reflects recent intake of Se; optimal Se concentration is age dependent.


Fasting morning values of plasma Zn <70 μg/dL on more than one occasion require further investigation.


Plasma preferred over serum.


Zn level declines with elevating C-reactive protein.


COMMENTS


NOTE: Reference values may vary by laboratory PEDIATRIC MALNUTRITION INDICATORS


LABORATORY ASSAYS FOR VITAMIN AND MINERAL STATUS


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