SIGNS/SYMPTOMS NAILS (continued)
Muehrcke lines two transverse white lines parallel to the lunula in the nail bed; temporarily disappear with pressure
Mees lines
transverse white lines in nail plate; usually not on thumb; do not disappear with pressure
Other: Malnutrition^
Possible non–nutrition-related causes: Nephrotic syndrome • Glomerulonephritis • Liver diseases • Metabolic stress • Chemotherapy
Additional information: Apparent leukonychia Toxicity: Selenium
Possible non–nutrition-related causes: Poisoning (arsenic, carbon monoxide, thallium, or chronic fluoride) • Infections • Hodgkin lymphoma • Acute myeloid leukemia • Chemotherapy • Systemic lupus erythematosus
Additional information: True leukonychia
Koilonychia spoon shaped, concave
Splinter hemorrhage
Brittle Nail Syndrome (BNS) brittle, soft, dry, weak or thin, split easily
• Onychorrhexis: longitudinal ridging of the nail matrix
• Onychoschizia: lamellar splitting of the distal free edge of the nail plate
Vertical ridges severe and raised ridges
Deficiency: Iron Deficiency: Iron (with or without anemia)
Possible non–nutrition–related causes: Diabetes mellitus • Systemic lupus • Raynaud disease • Hypothyroidism
Additional information: Considered normal if seen on toenails only
Deficiency: Vitamin C
Anemia: Iron Toxicity: Selenium
Possible non–nutrition-related causes: Endocarditis • Trichinosis • Vascular disease • Psoriasis • Lichen planus
Possible non–nutrition-related causes: Aging process • Exposure to moist conditions • Hypothyroidism • Raynaud disease • Systemic amyloidosis • Medications (chemotherapy agents, retinoids, antiretrovirals) • Dermatologic conditions
Additional information: Biotin supplementation shown to improve BNS
Additional information: Slight vertical ridges are normal with aging
POSSIBLE NUTRITION-RELATED CAUSES
ADDITIONAL INFORMATION
PEDIATRIC MALNUTRITION INDICATORS
MICRONUTRIENT EXAM: CLINICAL INTERPRETATION OF NUTRITION FOCUSED PHYSICAL EXAM FINDINGS
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