as well as the condition-specific genes. Tese condition-specific genes are usually discovered as such through large-scale clinical association studies, which show a statistical correlation between certain SNPs and the condition and in response to particular drugs.
Newly-Developed Panels Allow Safe And Effective Treatment Options Pain and cardio panels look into clinically relevant variations in opiate receptor and statin metabolizing genes, for instance, in conjunction with the cytochrome P450 metabolizer status of the patient to suggest an appropriate dosage of medication and dosage. For patients suffering from neu- ropsychiatric conditions such as schizo-
phrenia or psychosis, several genes whose functions are brain-specific are evaluated alongside the typical cytochrome P450 drug metabolism genes. Determining the individualized treatment for these patients is critical early on to avoid hospitalization. Genes involved in the biosynthesis and metabolism of dopamine, or the transport of serotonin, are examined for risk variants that can include insertion/deletions and/ or SNPs depending on the gene in ques- tion. Tere is significant interplay amongst the genes involved in these neurological conditions, and variants in one gene in combination with those in another may spell trouble (gene-to-gene interactions). It has been clinically shown that choosing the correct initial treatment for these patients is tantamount to a sustained drug effect and
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