Supplements 101 Resveratrol: The Benefits of the ‘French Paradox’ in a Pill!
soybeans, Japanese knotweed, white mulberry, pines and pomegran- ates. Resveratrol is most concentrated in the skin, seeds and stems of grape plants, particularly the pinot noir variety. Plants make this chemical as protection against pests and ultraviolet exposure. Inter- estingly, grape vines will drastically increase levels of resveratrol in response to gray mold, the same mold sometimes seen on strawber- ries. In humans, resveratrol is a potent antioxidant, anti-inflammatory and cardiovascular protectant with anticancer and anti-aging effects. It is known to protect the brain from effects of aging and plague formation.
R The Importance of Resveratrol & The French Paradox
Cardiovascular disease remains the main cause of death world- wide, making any effective preventative measure extremely compel- ling. The ‘French Paradox’ is a phenomenon where, despite the same risk factors as the average U.S. citizen, the French have a relatively low incidence of Coronary Heart Disease. The observation was puzzling until the discovery of resveratrol in red wine. The French consumed relatively large amounts of saturated fat, smoked ciga- rettes, and were not known to be avid exercisers but had much less heart disease than seen in the U.S. Yes, the French love their wine but what was it in their wine that, in turn, loves their hearts? Other countries where red wine is commonly consumed also demonstrate the French Paradox.
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esveratrol is a naturally occurring plant chemical categorized as a polyphenol and known to be a powerful antioxidant. It is famous for being in red wine but also is present in peanuts,
Reduce Your Risk for Cardiovascular Disease
Anyone with risk factors for cardiovascular disease could benefit from taking resveratrol. Engaging in preventative medicine by ac- tively addressing underlying blood vessel inflammation with antioxi- dants like resveratrol may decrease one’s risk of developing cardio- vascular disease. Recognized risk factors for cardiovascular disease include being overweight, having diabetes or high blood pressure, tobacco use, having high cholesterol, and consuming relatively high levels of alcohol, salt, and saturated fat. Research is demonstrat- ing that underlying inflammation is central to the development of cardiovascular disease and may be much more important to target in treatment than traditional high cholesterol levels. Through potentially lowering inflammation in the blood vessels, resveratrol should be a cornerstone therapy for cardiovascular disease prevention.
How Does Resveratrol Work in the Human Body?
Protection of the blood vessels occurs through resveratrol halting the inflammatory processes that contributes to atherosclerosis. Ath- erosclerosis is a buildup of plaque in artery walls. This plaque can eventually clog the artery lumen and lead to occlusion or blockage of blood flow like a boulder in a stream. A stroke can occur when a portion of the plague dislodges causing a blockage or damage like a tear further downstream along the circulatory system. It is absolutely astounding that a person does not typically have symptoms of the occlusion, pain for instance, until 90% of a blood vessel is blocked. Your body, in its innate wisdom, may be able to compensate and find other avenues for blood flow, called collateral circulation. At some point, the inflammation and atherosclerosis continues, leading to a cardiac event. This is why preventative measures like resveratrol are so crucial. One is unaware of the problem until it is too late and some damage has been done to the circulatory system.
Health Benefits of Resveratrol The many actions and mechanisms whereby resveratrol is useful
in the body include: antidiabetic (blood sugar stabilizer), decreases insulin resistance, antioxidant, anti-inflammatory, antiproliferative, antithrombotic, endothelial protectant, anti-obesity, reduces oxidized LDL, decreases cholesterol, increases bile acid excretion, and raises nitric oxide.
Drinking More Red Wine May Not be the Answer
The French Paradox has established that regular, moderate con- sumption of red wine is cardioprotective. Of course, any potential health benefit of an alcoholic beverage is very controversial. Putting the calories aside, heavy alcohol consumption is well known for many detrimental effects on the cardiovascular system. On the other
KARA BURKHART, ND
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