Omega-3s
In any strategy for mitochondrial membrane health, DHA and EPA, the omega-3 fatty acids from certain fish and marine life, are essential. These lip- ids keep membranes fluid, which makes mitochon- dria that function better and are less vulnerable to damage. Of the many studies demonstrating the protective benefit of Omega-3s for AD, one of the most impressive is the Rotterdam Study of 1997, which evaluated more than 5,000 participants aged 55 and older over the course of two years, and found that those with high fish consumption had lower risk of AD. To choose a good omega-3 sup- plement, look for a marine-sourced EPA/DHA from a manufacturer which adheres to pharmaceutical- level production practices, is third-party assayed for contaminants (mercury, arsenic, cadmium, dioxins, PCBs), and is stabilized with natural antioxidants. These products are often molecularly distilled, and the label specifies the marine animals from which the oils are extracted (e.g. salmon, cod, mackerel, calamari, sardines, herring, krill). Depending on need, daily intake of DHA ranging from 500 to 2000 mg and of EPA from 750 to 3000 mg is non- toxic and has benefit not just for the brain but for the whole body.
Mighty Mito-nutrition The interrelationships between ROS, brain mi-
tochondria, and specific nutrient antioxidants are complex, and it is becoming clear that not all an- tioxidants are equally good at protecting brain cell mitochondria from oxidative stress. Effective brain
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