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body. He says, “If we have a naive heifer that doesn’t have good an- tibody titers already existing, or hasn’t been exposed to natural dis- ease or to the vaccine, those virus- es can go to the ovary, the oviduct and the rest of the reproductive tract and cause an infl ammation that will last about 7 to 10 days. That can throw her off cycle and cause some other consequences. That’s why we don’t recommend using the modifi ed live virus at the same time you’re going to use a synchronization product in them, because it can upset that cycling mechanism and cause infertility for about one cycle.” In addition, the adjuvants placed
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in killed vaccines to make them work and the animals respond to them can also have side effects that may last up to 10 days; therefore, those vaccines should be applied before instead of at the time of breeding. “It takes a full 2 weeks, and
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sometimes up to 4 weeks, before we get antibodies from killed vac- cines up to the protective level that we need, so timing of administra- tion is important,” he says. “Also, if we start using ‘gram-negative’ vac- cines, which are common around cattle operations — they can be pinkeye, haemophilus, Pasteurella/ Mannheimia, vibrio, lepto or Bangs’ vaccines — too many of those types of vaccines given at the same time to heifers around the time of breed- ing can cause release of a product called endotoxin that’s inherent in those types of vaccines.” The effects of endotoxins can be
cumulative and throw the heifers off cycle, so those types of vaccines should be applied at least a month ahead of the breeding season or the beginning of a synchronization program.
42 The Cattleman January 2014
thecattlemanmagazine.com
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EQUAL PRESSURE = LESS INJURIES
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