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sagging tissues, it is useful to perform the combination treatment with volumising fillers using the cannula technique with appropriate vectors. It is important to use a volumising filler that has maximum purity, and good homogeneity and viscosity, giving the desired long-lasting lifting and volumising effect, with an even and natural looking result. In a more comprehensive aesthetic treatment


approach, the treatment regimen can involve other individual or maintenance aesthetic treatments such as chemical peels, mesotherapy, fillers, botulinum toxin A, LED therapy, photodynamic therapy, and surgical treatments.


The final improvement of the skin


is a gradual process and takes a number of weeks or even months. As the


treatment result is totally natural, it is important to take pre- and post- treatment photographs.


Conclusions The INTRAcel device provides a new possibility to combine bipolar and monopolar fractional RF microneedling and minimally ablative superficial RF treatments in the targeted multilayer mode during the same treatment session. It is an innovative treatment option for reducing the signs of ageing, acne, acne scars, scars and stretch marks. The treatment improves the texture of the skin, enlarged pores, reduces wrinkles, laxity and results in a younger, completely natural appearance and healthy skin. After the treatment one can almost immediately


resume the normal activities, full skin recovery being between 1 and 5 days. Individually adjustable treatment modalities, including treatment depth and energy level, selection or combination of monopolar RF and bipolar RF energies and available combination of needle and non-needle treatment arrays, safety profile and minimal downtime make INTRAcel a versatile device. Although INTRAcel treatments are considered to be relatively safe, in order to adjust the treatment protocol to the needs of the patient, the clinical applications require proper training and treatments should be performed by skilled professionals. In addition, more clinical studies are needed to reveal the full potential of the technology.


 Declaration of interest None. The author did not receive any remuneration from Jeisys Co in writing this article.


 Figure images © Dr Marge Uibu


Key points


n Fractional radiofrequency microneedling (FRM) is an innovative treatment option for reducing the signs of ageing, acne scars and stretch marks


n FRM improves the texture of the skin, enlarged pores, and reduces wrinkles and laxity


n FRM results in a completely natural appearance and healthy-looking skin


n FRM is an effective office-based treatment modality with a good safety profile and minimal downtime


n FRM is suitable for repetitive maintenance treatments and can be combined with any other aesthetic treatments


References


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2. Yoon J, Park D, Son T, Seo J, Nelson JS, Jung B. A physical method to enhance transdermal delivery of a tissue optical clearing agent: combination of microneedling and sonophoresis. Lasers Surg Med 2010; 42(5): 412–7


3. Alster TS, Lupton JR. Nonablative cutaneous remodeling using radiofrequency devices. Clin Dermatol 2007; 25(5): 487–91


4. Lolis MS, Goldberg DJ. Radiofrequency in cosmetic dermatology: a review. Dermatol Surg 2012; 28(11): 1765–76


5. Atiyeh BS, Dibo SA. Nonsurgical nonablative treatment of aging skin: radiofrequency technologies between aggressive marketing and evidence-based


efficacy. Aesthetic Plast Surg 2009; 33(3): 283–94


6. Cho SI, Chung BY, Choi MG et al. Evaluation of the clinical efficacy of fractional radiofrequency microneedle treatment in acne scars and large facial pores. Dermatol Surg 2012; 38(7 Pt 1): 1017–24


7. Seo KY, Yoon MS, Kim DH, Lee HJ. Skin rejuvenation by microneedle fractional radiofrequency treatment in Asian skin; Clinical and histological analysis. Lasers Surg Med 2012; 44(8): 631–6


8. Yeo UC, Lee DR, Lim SD. Histologic evaluation of deep dermal heating by fractional radiofrequency according to energy. ASLMS 30th Annual Conference 2010, Phoenix Convention Center, Arizona. Published in INTRAcel Articles Compendium, Jeisys 2012: 4–9


9. Kashlan LN, Hernandez C. Pain management in dermatologic procedures: before and after. Dermatol Surg 2012; 38(8): 1263–76


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