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| NON-INVASIVE REJUVENATION | ARTICLE The TCA solution is compounded in a weight to


volume preparation. To prepare a 35% solution, 35 g of TCA crystals are dissolved in a small amount of water, then further water is added to make a total volume of 100 mL. TCA is stable at room temperature and not light-sensitive. TCA peeling is a painful procedure; therefore, local


injection anaesthesia or intravenous sedation should be considered. A patient usually becomes completely comfortable 15–20 minutes after the procedure, when the frosting subsides. During the procedure, TCA is painted using a q-tip


according to the cosmetic units and until a white frost appears. The degree of the frosting correlates with the depth of solution penetration: ■ Level I is speckled white frosting with mild erythema and corresponds to superficial penetration


■ Level II is characterised by an even white-coated frost with background erythema. This degree of frosting is usually desirable for medium depth peels


■ Level III is solid white opaque frost with little or no background erythema, usually characterising deep peels and not desirable in a TCA procedure. During the first few days after the peel, patients are expected to feel a tightening and swelling of the skin, as


The main


indications for deep chemical peels include


dyschromia, fine and coarse wrinkles,


pre-malignant skin tumours, and acne scars.


well as a gradual crusting and darkening. On day 3 or 4 post-peel, the skin starts to crack and desquamation begins. Full re-epithelisation is usually complete after 5–7 days (Figure 2). A 35% TCA peel can be combined with Jessner’s


solution (resorcinol 14%, lactic acid 14%, and salicylic acid 14% in alcohol), solid CO2


10, or 70% glycolic acid11 .


Deep peels The main indications for deep chemical peels include dyschromia, fine and coarse wrinkles, pre-malignant skin tumours, and acne scars. Deep peeling solutions penetrate to the mid-reticular dermis and create the maximum effect for the production of new collagen. The solutions for deep peels are composed of a combination of croton oil and phenol at different concentrations. Phenol is an aromatic hydrocarbon originally derived from coal tar. Croton oil is an extract of the seed of the plant Croton tiglium, which causes skin vesiculation. Other chemicals in use in deep chemical peel formulae include septisol, water, and vegetable oils (glycerin, olive, sesame)12


. A phenol-based peel is carried out under full


cardiopulmonary monitoring with intravenous hydration throughout the procedure. Intravenous


prime-journal.com | November/December 2012





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