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ARTICLE | DERMALREJUVENATION |


the skin’s surface. Therefore, the risk of post- inflammatory pigmentation disorders is reduced, and the microneedling treatment modality is suitable for all skin types. Furthermore, the barrier function of the skin is preserved, enabling a quick recovery. The INTRAcel device was originally developed to


developed by the devices, which diminishes the tissue


burns and allows for a safer treatment profile. RF has been used in aesthetic skin treatments for


more than 10 years. It has been shown to stimulate the restructuring of collagen and elastin, resulting in better skin quality and the reduction of wrinkles3, 4


. The


energy levels used in non-invasive RF devices have been limited to the tolerance of the epidermis. Therefore, the energy levels in the deeper dermis have been relatively low, resulting in a sub-optimal dermal heating effect. Subsequently, the results of


RF has been shown to stimulate the restructuring of collagen and elastin,


resulting in better skin quality and the reduction of wrinkles.


non-ablative RF procedures have generally been moderate5


. Fractional RF microneedling technology


(FRM) overcomes this problem, targeting different levels of the dermis without inducing heat damage to the surface of the skin. This enables an effective treatment with a better safety profile. FRM has been reported to give good clinical results in the treatment of acne scars and large facial pores6 side-effects.


, and rejuvenation7 with minimal


INTRAcel The original INTRAcel device (Jeisys Co, Seoul, South Korea) uses 49 partly insulated microneedles targeting bipolar RF (FRM-bipolar) at variable pre-selected depths into the skin. The depth of the treatment can be selected between 0.5–2 mm and the RF emission is adjustable to seven levels ranging between 0–2.4J. The energy deposition takes place within 0.04–0.1 seconds. Each needle has an insulated coating, allowing the release of thermal effect only from the tip of the needle, preserving


52 ❚


Figure 2 Female patient, aged 42 years, showing the first signs of ageing. Before (A, B, C) and after (D, E, F) two INTRAcel treatment sessions


sessions), and fractional CO2 (10 sessions)


Figure 1 Severe acne scars, before and after six INTRAcel treatment sessions. Previous treatments were mechanical abrasion, ablative CO2


(three


treat acne scars and acne, but it was soon noticed that it can also be successfully used for rejuvenation treatments, other scar types, and stretch marks. It improves skin texture, fine lines, deeper wrinkles, and skin laxity. The second generation All New INTRAcel device is a three-fold treatment platform that includes monopolar fractional microneedling (FRM-monopolar), bipolar fractional microneedling (FRM-bipolar), and minimally ablative superficial RF rejuvenation (SRR). The monopolar RF can go deeper than bipolar RF. As skin impedance influences RF delivery, the new INTRAcel device includes an impedance monitoring function, automatically calculating the output value. This function is essential for safe and effective intradermal monopolar RF delivery. Each treatment modality can be used individually, as well as in combination. Absolute contraindications for the treatment include


pacemaker, previous use of gold thread skin rejuvenation, keloid formation constitution, and skin infections.


Clinical applications Rejuvenation The INTRAcel single-use microneedle treatment tip has 2000 pulses and one can select between bipolar and monopolar RF treatment mode. For the best results, multiple treatment passes with a 50% overlap at different depths and vector directions are used. According to the preliminary biopsy studies reported by Jeisys8


, lower


energy delivery in FRM-monopolar mode seems to achieve the thickening of the collagen fibres, while higher energies seem to up-regulate fibroblast production in FRM-bipolar mode. The bipolar and monopolar microneedling can be


combined with the minimally-ablative superficial RF (SSR) treatment option for a more superficial effect. The


November/December 2012 | prime-journal.com


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