jaaha.org / JAAHA
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ORIGINAL STUDIES
A Novel Method of Core Aspirate Cytology Compared to Fine-Needle Aspiration for Diagnosing Canine Osteosarcoma
SA Neihaus, JE Locke, AM Barger, LB Borst, RL Goring
ABSTRACT There is little information in veterinary literature regard- ing the diagnostic accuracy of aspirate cytology for the diagnosis of canine osteosarcoma (OSA). The authors compared the diagnostic accuracy of a novel method of cytologic collection, termed core aspirate cytology (CA), with fine needle aspiration (FNA) and histopathology in 27 dogs with lytic and/or proliferative bone lesions. Alkaline phosphatase (ALP) staining was performed to confirm the diagnosis of OSA cytologically. OSA was accurately diagnosed in 85% and 95% of FNA and CA, respectively. ALP staining was 100% sensitive for the di- agnosis of OSA. CA using a bone marrow biopsy needle allowed for penetration of cortical bone and aspirate cytology with a larger bore needle than FNA; however, there was no significant difference in diagnostic accu- racy between techniques. Aspirate cytology with ALP staining was a safe, accurate, and minimally invasive diagnostic test for the evaluation of suspected OSA le- sions in dogs.
RETROSPECTIVE STUDIES
Canine and Feline Epileptic Seizures and the Lunar Cycle: 2,507 Seizures (2000–2008)
L Browand-Stainback, D Levesque, M McBee
ABSTRACT Epileptic seizures in 211 canine and feline patients diag- nosed with idiopathic epilepsy were evaluated for tempo- ral significance in relation to the lunar cycle. Seizure counts were compared among each of the eight individual lunar phases, among each of eight exact lunar phase dates, and by percent of lunar illumination using generalized esti- mating equations. No statistical significance was found in any of these comparisons excluding a relationship be- tween the onset of epileptic seizures and the phases of the moon. Alteration in anticonvulsant treatment or monitor- ing of canine and feline patients with idiopathic epilepsy at large was not warranted based on the lunar cycle.
RETROSPECTIVE STUDIES
Partial Resolution of Hypoplastic Trachea in Six English Bulldog Puppies with Bronchopneumonia
DL Clarke, DE Holt, LG King
ABSTRACT Six English bulldog and nine nonbrachycephalic pup- pies with bronchopneumonia and radiographs were evaluated. Relative size of the trachea was measured by the tracheal diameter (TD) and the thoracic inlet dis- tance (TI), expressed as a ratio (TD:TI). At diagnosis of bronchopneumonia, there was a significant difference between the median TD:TI of the bulldog puppies (0.07; range, 0.06–0.09) and that of the nonbrachycephalic puppies (0.14; range, 0.11–0.25; P=0.0004). At the same time, there was also a significant difference be- tween the mean TD:TI of bulldog puppies (0.07±0.01) and that of nonbrachycephalic puppies (0.15±0.05; P=0.002). Follow-up radiographs showed significant increases in TD:TI ratio in all six bulldogs (median TD:TI = 0.14; range, 0.12–0.18; P=0.03 and mean TD:TI = 0.15±0.02; P=0.0007), whereas the ratio did not change significantly in the nonbrachycephalic control group (median TD:TI = 0.17; range, 0.14–0.22; P=0.10 and mean TD:TI = 0.18±0.03; P=0.06). Tracheal hypo- plasia in some brachycephalic dogs might partially or completely resolve with growth to mature body size.
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jaaha.org for more information. Trends magazine, September 2011
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