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Imaging


70


Drug Discovery World Summer 2011


Table 1: Summary of the in vivo preclinical product offerings of the companies reviewed Aspect Of In Vivo PreClinical Imaging Supported:


Imager Modalities Offered: Magnetic resonance imaging (MRI) Optical (bioluminescence/luminescence) Optical (fluorescence)


Positron emission tomography (PET)


Single photon emission computed tomography (SPECT) X-ray


X-ray computed tomography (CT) Ultrasound (US)


Multi-Modality Imaging Combinations: On the same instrument


Via co-registration on different imagers


Imaging Reagents: Fluorescent Imaging Reagents (including near IR) Bioluminescent Imaging Reagents


Light producings animals, cell lines or microorganisms PET Radioactive Tracers MRI Contrasting Reagents


X-Ray CT Contrasting Reagents SPECT Probes


Ultrasound Contrasting Reagents X X X


Aspect Imaging


X


X X


X X X


X


X X


X2


Berthold Technologies BioScan


Caliper Life


Sciences


Carestream Molecular Imaging


X X X


X3 X


XX X


X LI-COR Biosciences


Miltenyi Biotec PerkinElmer Promega


Siemens Preclinical X X X


XX X


X X X6


X1 XX X X


X X X X


X X X


X X X X


X4 X X


X4 X5


Notes: 1 Lumi. + Fluor.; 2 Cherenkov optical of PET tracers; 3 Including radio-isotopic imaging; 4 Coming soon ; 5 Ultrasound microbubbles; 6 Photoacoustic Imaging. X X x XX X


X X


X X


X X X


X X


Sofie Biosciences UVP


Visual Sonics


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