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For adults with diabetes


Ready for an around-the-clock insulin that you can take on your time?


• Only once-daily Tresiba® allows adults to change their long-acting


insulin day-to-day dose timingª Adults who miss or delay a dose should take Tresiba®


as soon as they remember, then continue


with their regular dosing schedule, making sure there are at least 8 hours between doses • Tresiba® provides blood sugar control for more than 24 hours,b • Tresiba® releases slow and steady, and works the way the body’s insulin does • Once in use, Tresiba®


lasts 8 weeks—twice as long as the Lantus®


discarded after 4 weeksc aIn 2 clinical trials, Tresiba®


bIn studies, Tresiba® cIn-use Tresiba®


was studied at alternating dosing intervals. has been shown to work effectively beyond 42 hours, after 8 once-daily injections. can be kept at room temperature (below 86°F), away from direct heat and light, or refrigerated (36°F to 46°F).


What is Tresiba® • Prescription Tresiba®


• Tresiba® • Tresiba®


? is a long-acting insulin used to


control high blood sugar in adults and children who are 1 year of age and older with diabetes


is not for people with diabetic ketoacidosis is not for children who need less than


5 units of Tresiba® • Tresiba® each day


• It is not known if Tresiba® children under 1 year of age


is safe and effective in


is available in 2 concentrations: 200 units/mL and 100 units/mL


Important Safety


Information Do not share your Tresiba®


FlexTouch® with


other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.


Who should not take Tresiba® Do not take Tresiba®


if you:


• are having an episode of low blood sugar • are allergic to Tresiba®


Tresiba® Before taking Tresiba®


or any of the ingredients in , tell your health care


provider about all your medical conditions, including if you are:


• pregnant, planning to become pregnant, or are breastfeeding


• taking new prescription or over-the-counter medicines, vitamins, or herbal supplements


Talk to your health care provider about low blood sugar and how to manage it.


How should I take Tresiba® ?


• Read the Instructions for Use and take Tresiba® exactly as your health care provider tells you to


Available by prescription only. FlexTouch®


, NovoFine® , NovoTwist® ? with powerful A1C reduction pen, which must be


Ask your health care provider today if you’re Tresiba®


• Do not do any conversion of your dose. The dose counter always shows the selected dose in units


• Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to


• Adults - If you miss or are delayed in taking your dose of Tresiba®


:


o Take your dose as soon as you remember, then continue with your regular dosing schedule


o Make sure there are at least 8 hours between doses


• If children miss a dose of Tresiba® :


o Call the health care provider for information and instructions about checking blood sugar levels


more often until the next scheduled dose of Tresiba®


• Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them


• Do not reuse or share your needles with other people. You may give them a serious infection, or get a serious infection from them


• Never inject Tresiba® pen into a vein or muscle


• Never use a syringe to remove Tresiba® FlexTouch®


affects you from the What should I avoid while taking Tresiba® ?


• Do not drive or operate heavy machinery, until you know how Tresiba®


• Do not drink alcohol or use prescription or over-the- counter medicines that contain alcohol


What are the possible side effects of Tresiba®


? Tresiba® may cause serious side effects that can


be life-threatening, including: • Low blood sugar (hypoglycemia). Signs


If you need assistance with prescription costs, help may be available. Visit pparx.org or call 1-888-4PPA-NOW.


, and Tresiba® All rights reserved. Ready.


and symptoms that may indicate low blood sugar include anxiety, irritability, mood changes, dizziness, sweating, confusion, and headache


• Low potassium in your blood (hypokalemia)


• Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Tresiba®


. Tell your


health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain


Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness.


Common side effects may include reactions at the injection site, itching, rash, serious allergic reactions (whole body reactions), skin thickening or pits at the injection site (lipodystrophy), weight gain, and swelling of your hands and feet.


Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.


Please see Brief Summary of Prescribing Information on the adjacent page.


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.


Recommended for use with NovoFine® of the shortest, thinnest needles available.d


Plus 32G Tip, one


Needles are sold separately and may require a prescription in some states.


d Tresiba® FlexTouch® can also be used with NovoTwist® needles. Visit Tresiba.com or call 1-866-739-1875 for more information. are registered trademarks of Novo Nordisk A/S.


Novo Nordisk is a registered trademark of Novo Nordisk A/S. All other trademarks, registered or unregistered, are the property of their respective owners. © 2017 Novo Nordisk


USA17TSM00092a May 2017 insulin degludec injection 100 U/mL, 200 U/mL


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