DEMENTIA CARE
The conventional view is that genes play a big part and that factors under your control, including diet, lifestyle and your health status, account for up to 40% of risk. This means up to 40% of dementia cases could be prevented or delayed. Genes actually account for less than 1% of cases of Alzheimer’s. But a new study, following 344,000 people over 15 years from the UK BioBank estimate that “up to 73% of cases could be prevented” by targeting risk factors largely under our control.
While the BioBank study didn’t include blood test measures of either homocysteine or omega-3, scientists at the US National Institutes of Health have attributed 22% of the risk of Alzheimer’s to raised blood homocysteine and 22% to a lack of omega-3.
Professor Smith’s group at Oxford University have tested the effects of giving B vitamins versus placebo to those with pre- dementia and found that the supplements halved the rate of brain shrinkage in one year and virtually stopped further memory loss.
“Increased omega-3 cut risk of
dementia or cognitive decline by around 20%.”
The authors of the study, published in the Nature Human Behaviour journal, investigated 210 modifiable risk factors. They found that increasing hand grip strength, a good reflection of physical strength, increasing leisure or social activities or time spent in sports clubs or gyms, spending less time watching TV or on a computer, having better dental health, drinking more water, not dozing off in the day and sleeping between seven to nine hours a night, not smoking or being exposed to smoke and having better lung function were all associated with less risk.
Being unemployed, or having a low income, having diabetes, high blood pressure or having had a stroke or brain injury all increased risk. Inheriting the so-called ‘Alzheimer’s gene’ ApoE4 didn’t make any significant difference to overall risk.
However, even this figure of 73% may be an under-estimate as this study excluded blood test measures. Professor David Smith from the University of Oxford, one of the study authors said: “We have probably under-estimated the power of prevention. Even this figure of up to 73% of cases preventable could be higher if a person’s omega-3 and B vitamin status, measured, by a blood test for homocysteine were taken into account.”
“The greatest effect we found in our trial was in those in the top third of DHA for the blood level of DHA (an omega-3), found in fish. Those with high DHA given B vitamins reduced their rate of brain shrinkage by 73%, down to the level normally seen in older people with no loss of cognitive function. They also had virtually no further memory loss and almost a third ended the trial with no clinical dementia rating at all.”
The benefit of omega-3 was also confirmed in a major study this year of over 100,000 people, finding that increased omega-3 cut risk of dementia or cognitive decline by around 20%. An increase in intake of omega-3 DHA of 200mg, which is what is found in either a serving of fish or a fish oil supplement, decreased risk by almost a fiſth.
“Up to 73% of Alzheimer's could be prevented by targeting risk factors largely under our control.”
One charity taking prevention seriously is the charity Food for the Brain. They offer, at
foodforthebrain.org, a free online Cognitive Function Test. Over 400,000 people have taken the validated Cognitive Function Test, which not only shows a person their cognitive status right now, but also their future risk, what’s driving future risk and what they can easily do right now to lower it.
https://foodforthebrain.org
x.com/TomorrowsCare
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