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INSTRUMENTATION • ELECTRONICS


S SENSORS OPHISTICATED


Carsten Koska reports on high-precision conductivity measurement at extreme temperature diff erences


C


onductivity sensors used in hygienic applications have to withstand regular cleaning in place (CIP) and sterilisation in place


(SIP) processes as well as related strong temperature diff erences. T is is why Ever Pharma Jena uses extremely robust conductivity sensors from a well-known expert in the sector for its extensive operations. Ever Pharma Jena, which was founded in 1950 as VEB Jenapharm and had operated under the name Jenahexal until its acquisition by the Austrian pharmaceutical manufacturer Ever Pharma in 2011, has specialised in the production of aseptic and sterilised preparations in pharmaceutical phials, vials and pre-fi lled syringes. Today, the annual production capacities of the company amount to 130 million units. T e product range includes neurological products, analgesics and hormones mainly for clinic supplies. Ever Pharma Jena specialises in crystal suspensions as well as on hormone preparations, which are produced in strictly separate plants due to the risk of contamination.


EFFICIENT CIP/SIP PLANT Because of the wide range of products including diff erent active substances, the fi rm decided on a process design where the preparation tanks in the production aren’t connected with the fi lling via a static pipe system. Instead, the plant sections are decoupled through the use of mobile sterile fi ltrate tanks. “T is allows us to have a signifi cantly more fl exible production at a higher product variant,” explains Martin Reuther, project manager at Ever Pharma Jena. To establish this process, the company put a new CIP/ SIP plant into operation in 2013. T is cleaning plant is capable of separately cleaning two sterile fi ltrate tanks at the same time. If needed, a third cleaning station can be activated. T e design results in large time savings with 54 tanks temporarily in alternating use and requiring regular cleaning and sterilisation.


Ever Pharma uses Knick’s sensors in its SIP and CIP applications


54 www.engineerlive.com


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