Proteomics, Genomics & Microarrays
Game-changing Platform Automates Genomics Liquid Handling
The firefly from SPT Labtech is an innovative liquid handling platform for next-generation sequencing (NGS) library preparation. firefly transforms NGS liquid handling workflows by bringing together pipetting and dispensing within a compact all-in-one design. Along with its hardware capabilities, the platform sets a new standard in powerful, intuitive liquid handling software with multiple user levels, intelligent programming and a fully transparent audit trail. A complementary peer-to-peer cloud-based network- the first of its kind- will allow researchers to share their custom protocols, as well as benefit from SPT Labtech’s validated tools to underpin scientific collaboration and innovation. The launch of firefly builds on SPT Labtech’s strong track record in engineering solutions for genomics applications.
Paul Lomax, Genomics Product Manager at SPT Labtech said: “While advances in next-generation sequencing have revolutionised the genomics field, library preparation methods remain a significant bottleneck for many laboratories. Liquid handling automation offers substantial throughput advantages, overcoming the need for multiple instruments, significant lab space, and high levels of investment. With its all-in-one capabilities, compact design and innovative software, firefly offers a step-change in productivity for genomics laboratories- at an affordable entry point.”
firefly comes application-ready for library preparation kits NEBNext Ultra II DNA; NEBNext Ultra II FS DNA; NEBNext Ultra II RNA, and Illumina DNA Prep with an extended range already under active development.
David Newble, CEO, at SPT Labtech, added: “Our team applies ingenuity to overcome customers’ workflow challenges and accelerate research. We are excited about the potential of the accessible, cost-effective firefly instrument to further democratise the adoption of liquid handling automation for NGS applications. Collaboration is a cornerstone of innovation, and by enabling peer-to-peer knowledge sharing, we aim to empower bigger genomics breakthroughs and advance health.”
More information online:
ilmt.co/PL/ZZma 57232pr@reply-direct.com
CE-IVD Marked Next-Generation Sequencing System
The CE-IVD marked Ion Torrent Genexus Dx Integrated Sequencer from Thermo Fisher Scientific, is an automated, next-generation sequencing (NGS) platform that delivers results in as little as a day. Designed for use in clinical laboratories, the fully validated system enables users to perform both diagnostic testing and clinical research on a single instrument.
“Next-generation sequencing has become an essential tool to bring the promise of precision medicine therapies to patients. With the automated, easy-to-use Genexus Dx Integrated Sequencer, any hospital - including regional and community hospitals - can bring NGS in-house, giving clinicians access to timely, comprehensive genomic profiling results,” said Garret Hampton, President, Clinical Next- generation Sequencing and Oncology at Thermo Fisher Scientific. “With faster answers, the results can aid clinicians in their patient management decision making which may include therapeutic options.”
In support of increasing physicians’ access to rapid NGS results, Thermo Fisher is also developing a complete sample-to-report diagnostic workflow and a portfolio of clinically validated assays, including those for comprehensive genomic profiling and haemato- oncology, on the Genexus System.
Thermo Fisher introduced the Ion Torrent Genexus System for research use only in 2019 as the first fully integrated NGS platform that delivers results in as little as 24 hours. The platform’s automated workflow minimises user intervention and the potential for human error, making NGS accessible for all labs.
More information online:
ilmt.co/PL/zqRL 57643pr@reply-direct.com
Automating Nucleic Acid Purifi cation Kit Protocols
Integra Biosciences has collaborated closely with nucleic acid extraction experts Macherey-Nagel (MN) to develop automated protocols for a variety of NucleoSpin® RNA and DNA extraction and purification kits on the ASSIST PLUS pipetting robot. The combination of these technologies provides high quality, purity and yield for DNA and RNA extracts from varied specimen types, suitable for use in a range of applications.
Each MN kit comes in a 96 well format, and can be easily automated on the ASSIST PLUS using a 12 channel 1250 μl VIAFLO electronic pipette with 1250 μl Sterile, Filter GripTips. Preset, biologically validated protocols can be quickly downloaded through VIALAB software, offering walk-away pipetting and incubation for:
MN NucleoSpin 96 RNA extraction kit - for extracting and purifying RNA fragments (>200 nt) from cell cultures, tissues and saliva in high throughput.
MN NucleoSpin 96 Tissue kit - for high throughput extraction and purification of high molecular weight genomic DNA from animal tissue samples or animal/bacterial cells.
MN NucleoSpin 96 Plasmid Kit - for parallel extraction and purification of high-copy plasmid DNA with a vector size of less than 25 kbp.
MN NucleoSpin 96 Plasmid Transfection-grade kit - for high throughput extraction and purification of high-copy, transfection-grade E. coli plasmid DNA with a vector size <25 kbp.
Automating liquid handling tasks using the ASSIST PLUS eliminates ergonomic hazards and provides more hands-free time for the user. Pipetting errors and variability between users are avoided, and the validated workflows consistency guarantee maximum reproducibility. In addition, the flexibility of this system ensures that it will always have a purpose in the lab, and can be used to simplify a wide range of general life sciences and diagnostics tasks for far-reaching applications.
More information online:
ilmt.co/PL/gPnP and
ilmt.co/PL/L2d9 58461pr@reply-direct.com
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