7


Jumping on the API bandwagon


We are now beginning to see other manufacturers looking to API techniques and, although they are a little less mature than ours, we anticipate rapid growth over the


next decade. Due to the combination of positive performance characteristics of APGC we fully expect the rapid growth in use of the technique across the coming decade.


We can find a good analogy for APGC in the LC-MS world, which began using electrospray ionisation to the point where, with MS/MS in particular, it became the gold standard for small molecule analysis. Why? Because ESI delivered high sensitivity and specificity for MS/MS. APGC looks set to follow the same path - and the helium issue will simply act as a catalyst. Overall, APGC-MS/MS offers an affordable, well-suited alternative to GC-MS/MS with electron ionisation for the determination of organic compounds at ultra-trace levels.


Final thoughts Figure 1. van Deemter curves for the three common GC carrier gasses.


The APGC system is a significant step up in terms of analytical performance relative to what we can currently achieve with EI systems. It represents a change in technology that aims to alleviate some of the biggest challenges the field currently faces. And, specifically with respect to helium shortages, APGC offers a simple plug-and-play solution for swapping to nitrogen - an affordable, renewable alternative that delivers results without any analytical compromise. We truly believe it is a gamechanger, and hope users will, too.


Read, Share and Comment on this Article, visit: www.labmate-online.com Innovative UV-sensitive mini-spectrometer


Hamamatsu Photonics has developed a UV-sensitive model in the ‘mini-spectrometer micro series’ that offers high sensitivity, fingertip size and low cost. These features help slash the size of environmental measuring instruments such as those needed for water quality monitoring and analysis. The C16767MA was designed and developed by leveraging the company’s unique micro-electro-mechanical system (MEMS) technology and advanced opto-semiconductor manufacturing technology.


The C16767MA separates UV light in the range of 190 to 440 nm or nanometers (one billionth of a meter) into multiple wavelengths and then simultaneously measures the light intensity at each wavelength. As just one application, for example, the C16767MA can be mounted in compact water quality monitors. Installing these monitors in rivers, lakes or oceans allows inspecting and analysing the content of multiple types of pollutants in water via absorption spectrophotometry. The C16767MA also assists in designing and manufacturing inexpensive water quality monitors that are easily installable in large numbers at many testing sites to monitor water quality, thus improving the accuracy of water quality assessment over broad-ranging areas. By expanding sales of the C16767MA, Hamamatsu Photonics will contribute to ensuring safer water and address climate change.


Sales of the C16767MA started on Wednesday 15 November 2023 for domestic and overseas manufacturers of environmental measurement instruments. The C16767MA was on display at ‘PHOTON FAIR 2023’, the all-inclusive Hamamatsu Photonics exhibition demonstrating the company’s advanced technologies and products along with the tremendous possibilities of light.


More information online: ilmt.co/PL/JRYZ and ilmt.co/PL/5BEm 61625pr@reply-direct.com


Mobile research-grade Raman microspectroscopy


Oxford Instruments WITec has unveiled alphaCART, a portable research-grade confocal Raman system, enabling researchers to conduct on-site chemical characterisation with the same speed, sensitivity, and resolution as WITec’s stationary instruments.


This innovative device combines a flexible, fibre-coupled Raman probe with a laser, spectrometer, and laptop computer, all housed in a sturdy portable case. It delivers excellent signal sensitivity, diffraction-limited resolution, and confocality. These capabilities allow for precise measurements both through and within transparent materials, making faint Raman signals visible even in high- background environments. Additionally, alphaCART includes integrated white-light illumination and a colour video camera for comprehensive sample assessment.


Researchers frequently conduct investigations in archaeology, the arts, cultural heritage, and geoscience in remote field settings or secure storage facilities. Similarly, experiments in materials science, process engineering, civil engineering, and gas analysis often take place outside traditional laboratory settings. alphaCART has been specifically designed to provide these researchers with uncompromised analytical capabilities while working in such challenging conditions.


According to WITec Product Manager Thomas Dieing: “alphaCART delivers the full performance of our industry-leading confocal Raman instruments on-site for samples too big, valuable or fragile to be moved. It can characterise paintings under protective glass, be brought into vaults for non-destructive analysis of priceless treasures, and peer through windows into reaction chambers for real-time chemical process monitoring.”


alphaCART utilises the modular design of the alpha300 microscope series, offering access to its complete range of upgrade options and accessories. It provides a choice of excitation lasers with different output wavelengths, including 532 nm, 633 nm, and 785 nm, with additional options available upon request. Users can also configure ultrahigh-throughput wavelength-optimised spectrometers, microscope objectives, and positioning hardware to suit their specific needs.


WITec’s alphaCART was unveiled to the public at the RAA 2023 International Conference on the Application of Raman Spectroscopy in Art and Archaeology, which took place in Athens, Greece from 6th to 9th September 2023.


More information online: ilmt.co/PL/qj1b 61134pr@reply-direct.com


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