55 Stable pH core-shell columns
Fortis Technologies SpeedCore pH+ is designed to offer extended pH stability compared to other core-shell particles. Designed around the companies SpeedCore particle, with a proprietary C18 bonding procedure, SpeedCore pH+ will deliver more stability than a traditional core-shell particle.
SpeedCore pH+
The new SpeedCore pH+ is available to scientists looking to operate in high pH liquid chromatography mobile phases. The use of high pH often
allows for the resolution and separation of more polar basic molecules, providing good peak shape and higher resolution than if basic analytes are analysed at low pH.
The sharper peak shape leads to higher recovery and sensitivity which provides better qualitative and quantitative results. The retention of a neutralised basic analyte leads to hydrophobic retention occuring which can lead to greater resolution between peaks as well as increased retention away from the column dwell-volume.
SpeedCore pH+ adds another selectivity to the range of SpeedCore columns that now numbers 11, including the SpeedCore BIO phases for peptide and protein separations.
For more information on this product and other novel solutions for LC and LC/MS please contact us.
Fortis Technologies supplies UHPLC and HPLC columns to the pharmaceutical, environmental and foodstuffs industries. Fortis Technologies driving goal is to supply innovative solutions to the separation and purification industries, utilising state of the art silica and bonding technologies at its UK site. A full range of stationary phases for every application is available; fully porous Fortis range for everyday robust applications, 1.7µm Fortis UHPLC columns for high resolution, sensitive methods. SpeedCore columns for fast efficient applications, FortisBIO columns for separation of peptides and proteins. All the columns are available in semi prep, capillary and analytical dimensions.
More information on this product and other novel solutions for LC and LC/MS can be found in the company’s Product Guide. Content includes solutions on unique selectivity, UHPLC particles, and high throughput with the companies PACE columns.
To request your free copy email us
technicalsupport@fortis-technologies.com or visit our website
www.fortis-technologies.com
Achieve Sharper Raman-based Microparticle Characterisation
WITec GmbH, the pace-setting leader in Raman microscope technology, has enhanced its ParticleScout automated particle analysis tool to offer even greater speed and versatility for finding, classifying and identifying microparticles.
ParticleScout now includes integration time optimisation that uses the signal to noise ratio to determine how long each particle is measured for identification. This not only greatly reduces overall measurement time, but also minimises the effects of fluorescence.
“The first release of ParticleScout was a response to the general demand for a microparticle analysis system built around Raman spectroscopy,” said Harald Fischer, Marketing Director at WITec. “This version is driven by direct feedback from researchers and their specific requirements in laboratories focused on environmental research, food science, pharmaceutics and many other applications.”
The enhanced ParticleScout has added image processing features such as vignetting correction, smart zoom that displays particle information dynamically depending on viewed area, and multiple sample area targeting. These conveniences are complemented by the integration and possible combination of dark-field, bright-field, epifluorescence and transmission sample illumination.
A software routine has been introduced to accelerate measurements of round samples such as filters that contain homogeneously distributed particles. It allows a wedge section to be selected for analysis and the results can then be extrapolated to represent the whole. Another innovation is the smart separation of closely adjacent or touching particles. This is especially useful for densely packed, heterogeneous samples.
Data post-processing with WITec’s TrueMatch™ Raman database management software is updated as well, including the ability to identify individual components in mixed spectra. Hit quality index (HQI) calculation is also optimised with automatic noise reduction and substrate spectra removal. Together these advances enable a new degree of precision in sample characterisation.
Finally, the quantitative report that summarises the results of a ParticleScout investigation can now be formatted with pre-configured templates such as tables, bar graph histograms or pie charts for clear and effective data presentation.
More information online:
ilmt.co/PL/9drA
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