table 2. Patient Characteristics for the First and Second Stages of the Study First Stage


Derivation (n=663)


Patient characteristics MDR-GNB culture


Age in years ± SD Age>70 years Male gender


LTCF or nursing-home residence Long-term hemodialysis


ICU admission in the last 3 mo Hospital discharge in the last mo Antibiotic exposure within 3 moc


Comorbidities Diabetes mellitus Malignancy


End stage renal disease Liver cirrhosis


Cerebrovascular accident Presence of bedsore


Central vascular catheterd Foley catheter


Previous recovery of MRSAe Previous recovery of VREe


No. 77


319 385 29 18 52


157 154


187 198 26 73


105 48 65 52 34 6


% 11.6a 66.0±17.2


48.1 58.1 4.4 2.7 7.8


23.7 23.2


28.2 29.9 3.9


11.0 15.8 7.2 9.8 7.8 5.1 0.9


142 192 26 14 19 72 68


85 98 16 37 52 22 29 26 11 4


No. 45


Validation (n=332)


% 13.6a 64.5±17.5


42.8 57.8 7.8 4.2 5.7


21.7 20.5


25.6 29.5 4.8


11.1 15.7 6.6 8.7 7.8 3.3 1.2


P


.379 .202 .111 .943 .024 .205 .221 .481 .327


.385 .910 .507 .949 .943 .721 .587 .995 .194 .739


No. 122


461 577 55 32 71


229 222


272 296 42


110 157 70 94 78 45 10


First Stage (n=995)


% 12.3a 65.5±17.3


46.3 58.0 5.5 3.2 7.1


23.0 22.3


27.3 29.7 4.2


11.1 15.8 7.0 9.4 7.8 4.5 1.0


490 533 19 55 71


357 394


281 383 89 47 99 77


180 40 32


111


vancomycin-resistant Enterococcus. aFrom initial surveillance culture or clinical culture obtained within 48 hours of hospital visit. bFrom clinical cultures obtained at the emergency department or during index hospitalization. cIncludes oral and intravenous antibiotic exposure for more than 48 hours. dIncludes Port-A catheter, Hickman catheter, long-term hemodialysis catheter (permcath), double-lumen catheter, and peripherally inserted central catheter. eWithin 1 year prior to the index blood culture.


All study patients


Second Stage (n=998)


No. 47


67.9±16.6


49.1 53.4 1.9 5.5 7.1


35.8 39.5


28.2 38.4 8.9 4.7 9.9 7.7


18.0 4.0 3.2


11.1 NOTE. MDR-GNB, multidrug-resistant gram-negative bacteria; LTCF, long-term care facility; ICU, intensive care unit; MRSA, methicillin-resistant Staphylococcus aureus; VRE, % 4.7b P


<.001 .001 .216 .039


<.001 .012 .985


<.001 <.001


.683


<.001 <.001 <.001 <.001 .561


<.001 <.001 .127


<.001


1220 infection control & hospital epidemiology october 2017, vol. 38, no. 10


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