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in her book, Seven Weeks to Sobriety that, “two-thirds of all alcoholics suf- fer from this potentially life-threatening disorder.” She also notes that situational/ psychological depression that results from the negative impact of AO can clear up once a drinker is sober and life improves. However, Larson lists these seven different sources of depression in alcoholics that have deep biochemical roots: neurotrans- mitter depletion, unavailability of pros- taglandin E1 (a fatty acid found in most tissues and organs, including the brain), vitamin/mineral deficiency, hypothyroid- ism, low blood sugar (hypoglycemia), food/chemical allergies, and candida- related complex (CRC/candidiasis).


Supportive Dietary Supplements


Before adopting a dietary supple- ment regimen to combat alcohol abuse or dependence, it is ideal first to obtain various tests that can allow for regimen customization. These tests include: Com- plete Blood Count (CBC) (anemia, infec- tions, blood disorders); Chemistry Profile [blood glucose, cholesterol, triglycerides, liver function (critical to monitor through- out AO treatment)]; Thyroid Function; Urinalysis (diabetes, chronic UTIs, kidney function); Glucose Tolerance Test; Zinc & Copper Levels; Candida-Antibody Panel; Serum Histamine Test; Food Allergy Test; Hair Analysis; Amino Acid Assay; Krypto- pyrroles Test (byproducts of hemoglobin synthesis that are excreted in urine and have no function in the body); and DHEA (if over age 40).


A full understanding of one’s health status can best inform an appropriate per- sonalized plan that includes the nutrients below found to be most supportive of alco- hol detoxification and sobriety. A holistic, nutritional approach focuses on detoxing the body to break the abuse/addiction, cor- recting the drinker’s body chemistry, and ensuring long term abstinence.


1.Vitamin B3 (Flush-Free Niacin/Nia- cinamide). Excess alcohol consump- tion increases the need for all of the B-complex vitamins, including vitamin B3, required to metabolize it. Abram Hoffer, MD, PhD, reports in The Vitamin Cure for Alcoholism that Vitamin B3 is also known to reduce brain levels of acetaldehyde. He further references one older, five-year study of 500 alcoholics in which niacin: (1) improved sleep, mood stability, and overall functioning of the subjects with the most serious symptoms; (2) significantly reduced tolerance to alcohol; (3) appeared to shorten greatly the course of acute toxic


brain syndrome; and (4) all but elimi- nated hypoglycemic reactions. Niacin is contraindicated in any drinker with abnormal liver function.


2.Vitamin C (as Ester-C). This antitoxin ac- celerates and improves the metabolism of alcohol’s toxic byproducts, thereby reducing alcohol-induced fatty liver and hepatitis, and reducing alcohol cravings and withdrawal symptoms.


3.Digestive Enzymes. AO interferes with pancreatic function, thereby blocking the release of the enzymes required for nutrient absorption. Critical pancreatic enzymes, combined with betaine hydro- chloride (stomach acid) and pepsin (a key stomach enzyme that breaks down proteins), enhance the effectiveness of nutritional therapy.


4.GLA (Borage Oil-Source of Omega-6 Fatty Acids). Gamma linolenic acid is an important brain lipid required for the formation of prostaglandin E1 (PGE1), a powerful antidepressant and anticon- vulsant. Since AO reduces production of GLA, the detoxing body requires supple- mentation to prevent alcohol withdrawal syndrome, depression, central nervous system impairment, and liver damage. Alcohol abusers’ long term use of this supplement is also indicated.


5.L-Glutamine. Although this amino acid is well-known as the precursor to the neurotransmitters GABA and glutamate, no recent research demonstrates its sup- port of alcohol abusers. Some holistic practitioners, however, report significant clinical substantiation for its role in sup- porting immunity and reducing alco- hol cravings (especially when applied directly under the tongue), anxiety, and insomnia in alcoholics.


6.Zinc Picolinate. AO causes the depletion and deficiency of zinc, a mineral known to prevent alcoholic liver disease.


7.Chromium Picolinate/Polynicotinate. Excess consumption of empty-calorie alcohol causes hypoglycemia when: (1) the over-taxed liver stops releasing glucose efficiently, (2) the pancreas over- compensates by overproducing insulin, which then removes too much glucose from the bloodstream, and (3) the chro- mium required to control abnormal glu- cose fluctuations is depleted. Chromium supplementation can stabilize both low and high blood sugar.


Additional supplements that support detoxification and longer term sobriety include a high potency multi-vitamin/ mineral, vitamin B6, calcium with mag-


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