Automation
maintenance and without any tools. Built upon the ELx405 Washer, the 405 Touch also offers all the features of this well-known product including its patented Dual-Action manifold, optimised cell washing for loosely adherent cell layers and patent pending Ultrasonic Advantage for self-maintenance of the washer’s aspiration and dispense tubes. A range of 405 Touch configurations is offered for dif- ferent sample processing requirements. All models can be automated with a BioStack Microplate stack- er or by integrating into a third party robotic sys- tem. 21 CFR Part 11 compliance is available with optional Liquid Handling Control Secure Software (Figure 13).
Figure 13
BioTek’s new 405 Touch microplate washer
BioTek’s (
www.biotek.com) new 405 Touch Microplate Washer incorporates a modern touch screen user interface for intuitive and flexible onboard instrument control of 96- and 384-well microplate washing. A graphical colour display guides users through protocol creation, instrument maintenance and wash protocol execution at the touch of a button. Predefined protocols for every- thing from ELISA and cell washing to vacuum fil- tration and biomagnetic separation for Luminex xMAP workflows allow washing immediately out of box. A context sensitive help system is a key press away whenever questions arise. Instructional videos walk users through instrument setup and basic use. A USB flash drive port enables convenient file transfer especial- ly helpful when an instru- ment is shared between researchers. Inte- grated buffer swi- tching within the washer’s main case allow for up to four buffers to be auto- matically primed and ready for use without taking up additional space on the lab bench. Quick-change manifolds enable wash modules to be quickly removed for
32 Figure 14: Caliper Life Sciences Sciclone NGS
Built on Caliper’s G3 platform, the Sciclone NGS leverages 25 years of industrial automation experi- ence with molecular biology expertise to provide a high-throughput solution for complex procedures to prepare nucleic acids for Next Generation Sequencing. Caliper Life Sciences (
www.caliperls. com) engages in true partnerships with its cus- tomers, offering pre-validated protocols as well as onsite customisation, training and sample valida- tion for application-specific workflows including targeted resequencing (both exome and custom panel), transcriptome expression profiling (RNAseq), and whole genome sequencing (WGS). The Sciclone NGS is compatible with all commer- cial kits, and works closely with industrial partners as well as key opinion leaders from the academic community to offer enabling solutions for life sci- ence researchers. The Sciclone NGS integrates three thermal control stations (0-110˚C) and a thermal shaker (0-70˚C) on to an enclosed 24-posi- tion deck, allowing true walkaway automation for the most complicated protocols, greatly reducing the variabil- ity associated with user-intervention. The 96-channel pipetting head offers precise liquid handling over a wide dynamic volume range (0-200µL), and an integrat- ed gripper for the movement of plates bet- ween on-deck thermal, shak- ing, and magnet positions. Unlike
Drug Discovery World Winter 2011/12
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