CELLULAR SCIENCES
a
b
Following these encouraging results, I requested that we embark on a five-site trial to determine if these initial findings were mirrored elsewhere, and also to see how feedback could improve the devices.2 The use of a micrometer (TruSlice Digital)
to set tissue slice thickness is innovative and its use on this device reminds us about how traditionally we have defined measurement and accuracy in the microtomy of histological sections from paraffin blocks. Clearly, in developing these devices, we have not re- invented the wheel but applied the concepts of well-trusted methodology to a different area of histological assessment. There is a need, however, to compare and
contrast the most promising devices in this area of investigation, simply to determine which will provide the best overall options for routine histological dissection. This is something that has not been performed to date. Owing to the complexity of, and variation in, tissue types dealt with in the modern histopathology laboratory, a single device that suits every need and eventuality with regard to dissection is perhaps an idealistic goal, but that is not an excuse for not trying. As Thomas Huxley said: “Science is simply common sense at its best”.
References 1 Orchard GE, Shams M, Nwokie T et al. Development of new and accurate measurement devices (TruSlice and TruSlice Digital) for use in histological dissection: an attempt to improve specimen dissection precision. Br J Biomed Sci 2015; 72 (3): 140–5.
2 Orchard GE, Shams M, Nwokie T et al. TruSlice and TruSlice Digital histological dissection devices, introducing an exciting development in providing improved accuracy and precision at the cut-up bench: data from a five-site trial throughout the United Kingdom. Br J Biomed Sci 2016. In Press.
Dr Guy Orchard, Consultant Grade Biomedical Scientist and Laboratory Manager, Viapath, St John’s Histopathology Department, St Thomas’ Hospital, London.
THE BIOMEDICAL SCIENTIST AUGUST 2016 427
Dissection devices: a) TruSlice; b) TruSlice Digital.
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