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46 May / June 2016 New Restek® Rxi®


-1301Sil MS GC Columns Are Ideal for MS Restek’s Rxi®


-1301Sil MS GC columns give you the selectivity you need without the bleed. These new columns offer true cyano phase selectivity along with highest thermal stability in the industry, which ensures you get dependable, accurate MS results and increased uptime. Improve the performance of existing methods for solvents, glycols, and other polar compounds with an Rxi® column.


-1301Sil MS GC


Typical cyano-based 1301 columns are well suited for the analysis of solvents across a range of volatilities; however, they are prone to high bleed and poor robustness, which limits their utility for MS work. The new Rxi®


-1301Sil MS column from Restek is a silarylene-based cyano stationary phase that not only provides the selectivity needed for analysing less volatile compounds, but it also has the highest thermal stability and lowest bleed, resulting in excellent MS compatibility. Exceptionally high thermal stability also allows for more aggressive thermal ramping to eliminate carryover of high molecular weight compounds between analyses (i.e., increased uptime).


In addition to providing both stable 1301 selectivity and the lowest bleed/highest temperature limits in the industry, the Rxi® is designed to provide maximum inertness. Each Rxi®


-1301Sil MS column -1301Sil MS column is tested with a QC mix that includes both acidic and basic probes


to ensure inertness across multiple compound classes. Greater column inertness improves peak shape and response, ensuring more accurate quantitative results.


-1301Sil MS column is ideal for the analysis of multiple compound classes across a range of polarities and volatilities. With its cyano-based selectivity and high thermal stability, it is the top performing 1301-type column for MS analyses.


The new Rxi® For more information visit www.restek.com


When contacting companies directly from this issue please tell them where you found their information.


Thank you


HALO BioClass for Fast, High Resolution Separations of Biomolecules


Kromasil ClassicShell Expanding opportunities


www.kromasil.com Chromatographic columns based on solid-core particles


for analysis in research and quality control laboratories.


HALO BioClass columns from Hichrom are specifically designed for fast, high-resolution separations of proteins, peptides and other biomolecules. The range currently includes three column types, HALO Protein, HALO Peptide and HALO Glycan columns. HALO Protein columns are especially suited to work involving intact proteins, monoclonal antibodies (mAbs), biosimilars and other large biomolecules such as pegylated proteins and antibody drug conjugates (ADCs). HALO


Peptide columns are designed for fast high resolution separation of peptides including peptide mapping (analysis of enzyme digest) for characterisation and monitoring of synthetic protein drugs and the analysis of therapeutic peptides and peptide biomarkers (protein surrogates). HALO Glycan columns are ideal for the HILIC separation of oligosaccharides, and particularly, of released and labelled glycans from glycoproteins and proteoglycans. A new HALO BioClass brochure has been published which contains technical details of all products.


For further information or a copy of this brochure please contact distributor Hichrom Limited on +44 (0) 1189 303660 or at technical@hichrom.co.uk.


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