1144 infection control & hospital epidemiology october 2015, vol. 36, no. 10
− − − − 3.57 (P<.001),
− −
figure 3. Relative proportion (A) and incidences (B) of healthcare-associated infections (HAIs) by major infection site in intensive care units (ICUs), 2001–2012. The incidence rate differences for BSI, pneumonia, and UTI were
1.96 (P<.001), and 0.66 (P<.001), 0.13 (P=.07), and 1.75
(P=.006) infections per 1,000 patient days, respectively, but the incidence rate for lower respiratory tract infection remained unchanged. In other types of HAI, the incidence rate differences for cardiovascular system infection; eye, ear, nose, throat, or mouth infection; gastrointestinal infection; central nervous system infection; and skin and soft-tissue infection were (P=.05),
0.05 (P=.45), +0.51 0.69 (P<.001), respectively. The incidence the categories of bone and joint infection, reproductive tract
infection, or systemic infection in the ICU settings each was <0.1 infections per 1,000 patient days. BSI, bloodstream infection; RTI, respiratory tract infection; UTI, urinary tract infection; SSI, surgical site infection; CDI, Clostridium difficile infection.
table 3. The Estimated Number of Healthcare-Associated Infections (HAIs) Prevented, Lives Saved, and Cost Savings at University of North Carolina (UNC) Hospitals, 2003–2012a
HAIs
Annual HAIs Prevented
−
BSI RTI UTI SSI
CDI All HAIs
31.7 14.0 33.0 9.5
20.9 79.4
Prevented, 2003–2012
−
285.0 126.3 297.0 85.3
188.5 714.2
Annual Lives Saved
−
3.9 2.0 0.8 0.3 0.6 4.5
Lives Saved, 2003–2012
−
35.1 18.2 6.9 2.4 5.4
40.7
difficile infection. aThe estimates were calculated using data from Online Table S1.
Hospitals in this study (2001–2012) and our previous study.19 A recent national prevalence survey described the importance of surveillance of other HAIs, including gastrointestinal infections due to C. difficile (12.1%) in the United States in 2011.11 At our
hospital, the incidences of cardiovascular system infections and skin and soft-tissue infections were significantly reduced, but because of the very low number of infections, the following incidences were not evaluated: bone and joint infections; eye,
Annual Cost Savings Low Estimate
−
230,758 275,573 28,448
112,600 134,226
1,630,607
Annual Cost Savings High Estimate
−
923,160 400,145 33,233
328,771 191,117
2,055,459
Cost Savings Low Estimate, 2003–2012
−
2,076,824 2,480,158 256,028
1,013,396 1,208,034 14,675,467
Cost Savings High Estimate, 2003–2012
−
8,308,438 3,601,301 299,096
2,958,940 1,720,053 18,499,131
NOTE. BSI, bloodstream infection; RTI, respiratory tract infection; UTI, urinary tract infection; SSI, surgical site infection; CDI, Clostridium
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