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PHARMANORD


Win the hay fever War this spring With pycnogenol!


With hay fever season just around the corner, you, as a pharmacist, knoW What's on the horizon. patients sneezing, coughing and Wheezing; runny noses; itchy eyes and even bronchial sWelling. there is neW hope on hand hoWever...


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any products and treatments exist to address these symptoms with varied


success. one such product however, is standing out for many positive reasons. With evidence supported benefits, more than 200 published trials and with contented users around the world, many hay fever sufferers are turning to pycnogenol® for reliable relief.


What is pycnogenol® ?


pycnogenol is a unique plant extract from the bark of the maritime pine trees (grown in sustainable french forests). key to many of its benefits, pycnogenol is a source of antioxidant plant compounds known as proanthrocyanadins which have been shown to help protect cells from free radical damage.


free radicals are created by our own bodies metabolism as well as from environmental factors such as smoking, air pollution and uv light


exposure. needed only in small amounts, free radical molecules can begin to cause cell and tissue damage if they are allowed to build up. free radicals can also play a role in hay fever symptoms, which is detailed later.


What happens during hay fever? allergies occur when the body's immune system has an exaggerated response to foreign particles which it (in most cases, mistakenly) perceives as harmful. in the case of hay fever, this foreign body is pollen (but animal hair, dust and detergents are other common allergies).


once in contact with the pollen, our mast cells (a type of white blood cell) release the hormone histamine throughout the body (particularly to the skin, nose, mouth, blood and lungs). free radicals in the body can further increase the amount of histamine produced by the mast cells


histamines trigger inflammation which in moderate levels, is actually a positive thing (as it encourages blood flow and transport of other compounds to help repair tissue). in the case of allergic response however, this inflammation is too great and can make it harder to breathe through constricted airways. histamines encourage the membranes of the nose to produce mucus, leading to the iconic runny nose and irritated throat.


through two main actions, pycnogenol has been shown to assist with hay fever in research: • anti-histamine reduction of free radical triggered histamine release. • anti-inflammatory, reducing the inflammation caused by histamines that are released.


pycnogenol the anti- histamine various trials have shown pycnogenol to have an anti-histamine effect,


combating this allergic response. the antioxidant compounds are able to neutralize free radicals, reducing the amount of histamine that's initially released from the mast cells. pycnogenol also increases the uptake of histamine into the storage component of the mast cells, rather than releasing them throughout the body where they would trigger inflammation (1)


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in a particular lab study, this antihistamine effect was demonstrated be more favourable than sodium cromoglycate, an antihistamine normally found in drop form (2)


pycnogenol the anti- inflammatory anyone who has ever experienced blocked sinuses, red irritated nostrils and constricted breathing will be well familiar with inflammation associated with hay fever. pycnogenol has demonstrated anti-inflammatory


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