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DRUG DISCOVERY AND DEVELOPMENT 39


of the top of the tablet.


n Consumer acceptance as the FFRE tablet has a softer look and is more appealing to the consumer and generally has a better mouth feel.


Tere are enough advantages of the FFRE tablet design over the FFBE design that it should be considered for all new tablet designs for coated and non- coated tablets, hence someday making the FFBE design obsolete.


Te same holds true with Concave Bevel edge tablets (CCBE) – Fig. 3 – commonly used on both round and shaped tablets to assist in reducing edge attrition during the coating process. Again, the radius edge would make a better and more robust design, generally allowing an increase in maximum compression force over the CCBE.


Designing tablets can be gratifying and provides a


Fig. 3. The concave bevel edge typically is a weaker tool design than the compound cup.


sense of ownership when all goes well. But when things go astray, it becomes anything but gratifying. A final tablet design should consider comments from all departments responsible. Considering comments from all departments will empower all involved and ensure a successful


and timely launch – and the enjoyment of an efficient, trouble-free tableting operation.


For more information ✔ at www.scientistlive.com/eurolab Dale Natoli is president of Natoli


Engineering Company Inc, St Charles, MO, USA. www.natoli.com


Eurolab-Micro-horz advert.indd 1


For more information ✔ at www.scientistlive.com/eurolab


02/05/2014 11:38:13


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