CATTLE RAISERS COMMUNITY
®
150 mg/mL ANTIMICROBIAL NADA 141-328, Approved by FDA For subcutaneous injection in beef and non-lactating dairy cattle only. Not for use in female dairy cattle 20 months of age or older or in calves to be processed for veal.
(gamithromycin)
Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. READ ENTIRE BROCHURE CAREFULLY BEFORE USING THIS PRODUCT.
INDICATIONS ZACTRAN is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle. ZACTRAN is also indicated for the control of respiratory disease in beef and non-lactating dairy cattle at high risk of developing BRD associated with Mannheimia haemolytica and Pasteurella multocida.
CONTRAINDICATIONS As with all drugs, the use of ZACTRAN is contraindicated in animals previously found to be hypersensitive to this drug.
WARNING: FOR USE IN CATTLE ONLY. NOT FOR USE IN HUMANS. KEEP THIS AND ALL DRUGS OUT OF REACH OF CHILDREN. NOT FOR USE IN CHICKENS OR TURKEYS. The material safety data sheet (MSDS) contains more detailed occupational safety information. To report adverse effects, obtain an MSDS or for assistance, contact Merial at 1-888-637-4251.
RESIDUE WARNINGS: Do not treat cattle within 35 days of slaughter. Because a discard time in milk has not been established, do not use in female dairy cattle 20 months of age or older. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
PRECAUTIONS The effects of ZACTRAN on bovine reproductive performance, pregnancy, and lactation have not been determined. Subcutaneous injection of ZACTRAN may cause a transient local tissue reaction in some cattle that may result in trim loss of edible tissues at slaughter.
ADVERSE REACTIONS Transient animal discomfort and mild to moderate injection site swelling may be seen in cattle treated with ZACTRAN.
EFFECTIVENESS The effectiveness of ZACTRAN for the treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni was demonstrated in a field study conducted at four geographic locations in the United States. A total of 497 cattle exhibiting clinical signs of BRD were enrolled in the study. Cattle were administered ZACTRAN (6 mg/kg BW) or an equivalent volume of sterile saline as a subcutaneous injection once on Day 0. Cattle were observed daily for clinical signs of BRD and were evaluated for clinical success on Day 10. The percentage of successes in cattle treated with ZACTRAN (58%) was statistically significantly higher (p<0.05) than the percentage of successes in the cattle treated with saline (19%). The effectiveness of ZACTRAN for the treatment of BRD associated with M. bovis was demonstrated independently at two U.S. study sites. A total of 502 cattle exhibiting clinical signs of BRD were enrolled in the studies. Cattle were administered ZACTRAN (6 mg/ kg BW) or an equivalent volume of sterile saline as a subcutaneous injection once on Day 0. At each site, the percentage of successes in cattle treated with ZACTRAN on Day 10 was statistically significantly higher than the percentage of successes in the cattle treated with saline (74.4% vs. 24% [p <0.001], and 67.4% vs. 46.2% [p = 0.002]). In addition, in the group of calves treated with gamithromycin that were confirmed positive for M. bovis (pre-treatment nasopharyngeal swabs), there were more calves at each site (45 of 57 calves, and 5 of 6 calves) classified as successes than as failures. The effectiveness of ZACTRAN for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica and Pasteurella multocida was demonstrated in two independent studies conducted in the United States. A total of 467 crossbred beef cattle at high risk of developing BRD were enrolled in the study. ZACTRAN (6 mg/kg BW) or an equivalent volume of sterile saline was administered as a single subcutaneous injection within one day after arrival. Cattle were observed daily for clinical signs of BRD and were evaluated for clinical success on Day 10 post-treatment. In each of the two studies, the percentage of successes in the cattle treated with ZACTRAN (86% and 78%) was statistically significantly higher (p = 0.0019 and p = 0.0016) than the percentage of successes in the cattle treated with saline (36% and 58%).
Marketed by Merial Limited 3239 Satellite Blvd., Duluth, GA 30096-4640 U.S.A. Made in Austria
®ZACTRAN is a registered trademark of Merial Limited. ©2012 Merial Limited. All rights reserved. Rev. 03/2012
INDUSTRY NEWS
TDCJ Ranch Managers Apply BQA Principles to 10,000-Plus Beef Cattle
T
EXAS AND SOUTHWESTERN CATTLE RAISERS ASSOCIATION (TSCRA) partnered with the Texas Beef Coun-
cil (TBC) and Texas A&M University AgriLife Extension to host a Texas Beef Quality Assurance Producer (TBQP) update for more than 45 Texas Department of Criminal Justice ranch managers in December. Representing more than 10,000 head of cattle, the ranch managers
learned the latest news in best management practices. The mission of the TBQP program is to promote good management
practices for cattle producers to strengthen consumer confi dence in beef as a wholesome food product. Educating Texas beef producers about beef quality assurance practices continues to be an essential part of the checkoff-funded program.
INDUSTRY NEWS
2013 — Conservation Banner Year By Spencer Miller, USDA Natural Resources Conservation Service
T
HE 2013 CONSERVATION NUMBERS SHOW THE IMPORTANCE OF VOLUNTARY, LOCALLY based conservation. Together, NRCS and conservation-minded farm-
ers, ranchers and other partners: • Developed conservation plans for more than 43.8 million acres. • Enrolled more than 279,000 acres into conservation easements, setting aside valuable wetlands, grasslands and farmlands. These landscapes help create wildlife habitat, clean air and water and lead to other en- vironmental benefi ts.
• Worked with producers in the Ogallala Aquifer region, the nation’s breadbasket, to implement conservation practices that use water wisely on more than 70,000 acres.
• Improved habitat for at-risk wildlife. Two initiatives geared toward the lesser prairie chicken and sage grouse put conservation practices on more than 220,000 acres and 570,000 acres, respectively.
• Assisted producers in the Mississippi River basin to improve water quality, restore wetlands and improve wildlife habitat on more than 255,000 acres.
• Helped landowners in 9 states improve sustainability and profi tability of longleaf pine forests, an iconic forest of the Southeast, on more than 50,000 acres. Learn more about NRCS and how conservation partnerships are ben- efi tting natural resources nationwide at
nrcs.usda.gov.
ZACTRAN-PI-thirdpage-MBovis_THE
CATTLEMAN_FA.indd 11/3/13 11:38 AM 30 The Cattleman March 2014
thecattlemanmagazine.com
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