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via chain scission according to the kinetic law (with k being the average rate constant for chain scission):


Mn = Mn,o x e -kt


The short second phase starts at a specific chain length and is characterised by the onset of volume and total mass loss via bioresorption. Unlike other degradable dermal fillers, the non-toxic oligomers resulting from total bioresorption of the Ellansé microspheres are completely excreted through normal metabolic pathways. This is the basis for the unique Ellansé dermal filler Family, differentiated only by the initial polymer chain length, offering tunable longevity. This has led to the creation of


the new and innovative products in the Ellansé Family, with clinical efficacy of 1, 2, 3, or 4 years, respectively.


Conclusions Superior to other dermal fillers,


Ellansé™, now available in over 60


countries worldwide, offers a unique combination of total and predictable bioresorbability and sustained performance for its entire Family, which is clinically proven.


Ellansé is an injectable


bioresorbable implant, indicated for deep dermal and subdermal implantation. It is a first in its class, next generation, biostimulatory dermal filler for patients who are not satisfied with the cost and inconvenience associated with frequent repetitive treatments for the same indication. Ellansé offers the maximum


potential for modelling and lifting owing to the combination of optimum viscosity, unique elasticity and uniform homogeneity. Furthermore, its three unique and technologically advanced features of sustained performance, tunable longevity and total bioresorbability (STAT Technology™), successfully overcome some of the significant shortcomings in the dermal filler arena and optimise many characteristics required in an ‘ideal dermal filler’. Ellansé-S (1 year), Ellansé-M (2 years), Ellansé-L (3 years) and


Ellansé dermal filler family longevity options The Ellans•  Key Features


■ Safety: PCL used in CE and US FDA approved medical devices for over 20 years


■ Bio-stimulatory dermal filler: strong presence of type I collagen


■ Fully bioresorbable: proven through radio-labelling studies


■ Sustained performance: maintained clinical effect ■ Tunable longevity: choice for both physician and patient


■ Cost-effective: for physician and patient


Ellansé-E (4 years) are specifically designed as a total customised solution for facial soft tissue augmentation, and can be used for a variety of indications. Patients


looking for longer-lasting and sustained results will benefit from Ellansé, creating customer satisfaction, leading to a higher patient retention rate.


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