LASERS AND LIGHTS |
P.L.E.A.S.E.® Professional: next-level laser technology for next-level therapies
L
aser treatments for cosmetic or aesthetic applications, and dermatology or drug delivery, have never
had this degree of medical precision. The recently launched versatile P.L.E.A.S.E.® (Precise Laser Epidermal System) Professional laser device from Pantec Biosolutions (Ruggell, Liechtenstein), offers applications across multiple industries that will soon experience the benefits.
Dermatological and aesthetic applications P.L.E.A.S.E.® Professional is a very compact but surprisingly powerful bench-top system combining new ground-breaking diode-pumped Er:YAG fractional ablative laser technology. The advanced pulse-forming capabilities enable safe and precise customised treatments that are well tolerated by patients. Accompanying treatment effects are greatly minimised and there is usually no need for local anaesthesia. P.L.E.A.S.E.® Professional offers advanced fractional ablation procedures with or without controlled heat profiles to perform skin rejuvenation and contouring treatments, with excellent and remarkable cosmetic outcomes.
Combination treatments This unique, flexible laser technology platform combines the advantages of both CO2
and Er:YAG and is also delivering outstanding
STEFAN SCHUBERT, Head BD and Sales, Dermatology, Pantec Biosolutions AG, Industriering 21, 9491 Ruggell, Liechtenstein
email:
stefan.schubert@pantec-
biosolutions.com;
website:
www.pantec-biosolutions. com and
www.please-professional. com
14 ❚ Product Portfolio |
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clinical results in skin rejuvenation through the medium of the newest fractional technology. The system can also be used for a wide range of applications in conventional dermatology, where it is ideally placed for highly effective combination therapies with selected topical treatments. The controlled and very precise intra-epidermal microporation delivered by P.L.E.A.S.E.® Professional increases skin permeability, making it ideal for the effective transdermal delivery of topical treatments or drugs with large molecular weights.
Conclusions P.L.E.A.S.E.® Professional is a
modern laser technology platform incorporating Pantec Biosolutions’ unique diode-pumped technology. This ground-breaking technology provides convincing clinical results to meet a wide range of clinical and aesthetic needs. P.L.E.A.S.E.® Professional is a comprehensive skin rejuvenation solution enabling a better, safer and faster cosmetic outcome for clients and patients with less pain and shorter downtime compared with any other available product. This remarkable system clearly
addresses the need to improve conventional dermatological applications and will open the door for completely new laser applications in the future, where the safety and precision of the technology make it more versatile than existing platforms.
'The P.L.E.A.S.E.® Professional laser is a nice and compact fractional Er:YAG laser. It is very versatile owing to its small size and offers many possibilities regarding selection of various parameters.'
DR MAURICE ADATTO, DERMATOLOGIE CHIRURGICALE ET ESTHÉTIQUE OF SKINPULSE DERMATOLOGY CENTRE, GENEVA, SWITZERLAND.
'In comparison with other lasers, the P.L.E.A.S.E.® Professional device is small and compact, but very powerful. Since it combines the advantages of CO2
and Er:YAG,
it is ideal for fractional skin rejuvenation procedures and many other potential applications. Patients experience a short downtime and similar side-effects as seen with other fractional lasers.”
DR CHRISTINE DIERICKX, DIRECTOR OF THE SKIN AND LASER CENTRE, BOOM, BELGIUM.
P.L.E.A.S.E.® Professional is a ground-breaking solution to highly sensitive drug delivery procedures. Its fractional ablative laser administers topically applied bioactive substances such as stem cells, antibodies and other therapeutics via skin microporation.
'My research group at the University of Geneva has been using the P.L.E.A.S.E.® device for 4 years. We have performed multiple studies to investigate potential therapeutic applications. To date, we have investigated more than thirty therapeutic drugs, ranging from small molecules such as lidocaine and diclofenac to larger mono- and polyclonal antibodies. From a drug delivery perspective, P.L.E.A.S.E.® Professional offers several advantages over existing systems. This device allows for controlled, individualised delivery of therapeutic agents in response to patient needs. It is possible to create hundreds, even thousands, of pores and the number of energy pulses used to create each pore — which determines dermal depth — can be programmed to ensure reproducibility. Both parameters enable fine tuning of the amount of drug delivered, as well as where it is administered within the skin.'
DR YOGESHVAR N. KALIA, SCHOOL OF PHARMACEUTICAL SCIENCES, UNIVERSITY OF GENEVA
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