11-04 :: April/May 2011
nanotimes News in Brief
Researchers at Arizona State University, USA, pre- sent in Science a strategy to design and construct self-assembling DNA nanostructures that define intricate curved surfaces in three-dimensional (3D) space using the DNA origami folding technique. A series of DNA nanostructures with high curvature – such as 2D arrangements of concentric rings and 3D spherical shells, ellipsoidal shells, and a nanoflask – were assembled.
COVER Schematic representations of DNA nano- structures with complex curva- tures including two-dimensional arrangements of concentric rings and three- dimensional shapes, inclu- ding a nanoflask 70nm tall and 40nm wide (DNA molecule is not shown to scale). © Dongran Han and Hao Yan, The Biodesign Insti- tute and Department of Chemistry and Biochemi- stry, Arizona State University / Science
Dongran Han, Suchetan Pal, Jeanette Nangreave, Zheng- tao Deng, Yan Liu and Hao Yan: DNA Origami with Complex Curvatures in Three-Dimensional Space, In: Science, Vol. 332(2011), No. 6027, April 15, 2011, Pages 342-346, DOI:10.1126/science.1202998:
http://dx.doi.org/10.1126/science.1202998
67
CEA-Leti and five partners are combining their ex- pertise to develop a self-powered cardiac pacema- ker eight times smaller than current models.
The Heart-Beat Scavenger (HBS) Consortium, which also includes the Sorin Group, TIMA, Cedrat Technologies, Tronics and EASII IC, is targeting an energy self-sufficient device that harvests me- chanical energy from the movements of the heart, eliminating the need for batteries and post-implant surgeries to replace them.
A longer-term goal of the project is to reduce healthcare expenditures. Heart failure represents one of the biggest public-health costs today in Euro- pe and the United States. Financed by the Minalo- gic competitive cluster in Grenoble, the HBS project goals include:
• Developing a self-powering pacemaker by harvesting the mechanical energy produced by the movements of the heart and eliminating the need for batteries that must be replaced every six to 10 years.
• Reducing the size of a cardiac pacemaker by a factor of eight, from 8 cm3
to 1 cm3 . This reduc-
tion will make it possible to attach the pacemaker directly to the epicardium, eliminating the need for intravenous introduction of cardiac probes.
http://www.leti.fr
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84 |
Page 85 |
Page 86 |
Page 87 |
Page 88 |
Page 89 |
Page 90 |
Page 91 |
Page 92 |
Page 93