articLe | DERMONUTRITION |
outcomeS of a dairy matrix product
ABSTRACT Introduction: In this perspective article, the authors briefly review the literature on dermonutrition (oral nutrition for skin benefits), and explore the effects of nutrients on skin condition, with a specific focus on the potential for nutrients to influence or improve of skin barrier function. A group of studies that explore the effects of dermonutrition stemming from a dairy product are then described in greater detail. The dairy product under review contains the following ingredients: borage oil, green tea polyphenols (GTPs), vitamin E, and a dairy matrix containing catechins together with probiotics: Lactobacillus casei, Lactobacillus bulgaricus, and Streptococcus thermophilus.
ANTHONY V. RAWLINGS founded AVR Consulting Ltd. in 2002 and is a leading consultant in the health and beauty industry, where he consults on functional skin care technologies. He is the author or co-author of more than 100 articles, book chapters and abstracts, and has filed over 50 patents in the areas of skin and food science.
email:
tonyrawlings@aol.com
KEYWORDS dermonutrition, nutrients, skin barrier function, natural mousirising factor, borage oil, linoleic acid, vitamin E, green tea polyphenols, filaggrin
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Studies: Relating to the dairy product under review, the studies described in this article include (i) in vitro skin studies examining the effects on epidermal differentiation and filaggrin expression; (ii) bioavailability studies on gamma linoleic acid and GTP; (iii) an open-label, double- blind, randomised efficacy study testing the effects of the ingredients on skin barrier enhancement; and (iv) an in vivo confocal Raman study in 60 women examining levels of natural moisturising factors (NMFs).
Conclusions:
The authors discuss the findings of these studies and conclude that the effects observed on epidermal differentiation, skin barrier function and NMF generation probably culminate from additive or synergistic effects of all the ingredients in the dairy product. This article is one of a few to explore the concept of using dermonutrition for skin moisturisation.
E. Krahn-Bertil, F. Hazane-Puch, and T. Lassel Danone Research, Palaiseau Cedex, France
Anthony V. Rawlings AVR Consulting Ltd., Northwich, Cheshire, UK
May 2011 |
prime-journal.com
a vital somatosensory interface (1). the skin also plays a vital role in regulating body homeostasis by reducing transepidermal water loss (teWL) to a minimum via the stratum corneum. It has been argued that skin barrier function is the
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most important function of the skin, which is modulated by many factors influencing its different properties. Indeed, intrinsic elements such as thickness of the stratum corneum, corneocyte size, corneocyte maturation, filaggrin, and natural moisturising factors (NMFs), as well as stratum corneum lipids (1), can influence skin barrier properties. Nevertheless, skin barrier function can be perturbed by environmental stressors, such as seasonal changes, pollution, and habits, and intrinsic factors such as ageing. Too much damage can enhance epidermal hyperplasia and inflammation (2). The most obvious solution to improve skin barrier function or to maintain its properties in barrier‑compromised conditions is treat by topical means. However, recent research
to
Skin moiSturiSation by dermonutrition:
Anthony V Rawlings reviews the outcomes related to a dairy matrix product, the effects of
nutrition on skin condition, and the implications of dermonutrition for skin moisturising
uman skin acts as a barrier between the internal and the external environment, protecting the body from mechanical damage, noxious substances, and penetration by pathogens and radiations, while being
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