AIR CONDITIONING, COOLING & REFRIGERATION
R454C and the next generation of data centre air conditioning
Sebastian Maron, senior product manager at STULZ, explains the advantages of using R454C refrigerant in recirculating air conditioning units and outlines the engineering considerations, operational benefits and long-term prospects for sustainable cooling in data centre environments
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s the world intensifies its efforts to mitigate the ongoing climate crisis, R454C refrigerant in recirculating air conditioning units has emerged as an effective
way to help data centre operators reduce their environmental impact. Offering lower global warming potential (GWP), improved energy efficiency and regulatory compliance with F-Gas Regulation 2024/573, R454C adoption also supports reliable operation and long-term sustainable cooling strategies.
Latest and greatest
First introduced in 2006, F-Gas Regulation 2024/573 is the latest version of the European Union (EU) law that controls fluorinated greenhouse gases (F-gases), such as hydrofluorocarbons (HFCs), which are used in refrigeration, air conditioning, heat pumps and aerosols. HFCs have a high GWP and F-Gas Regulation 2024/573 aims to reduce overall emissions by banning certain products, improving leak prevention and mandating proper recovery and recycling.
As part of their F-Gas Regulation 2024/573 compliance, data center operators must convert any air conditioning units in new installations to refrigerants with a GWP of less than 150 by 2027, otherwise they risk having their operating licence revoked. This can result in high costs due to corresponding penalties, while also having a negative impact on business development, as many customers only want to work with companies that can demonstrate a strong corporate social responsibility (CSR) strategy.
12 BUILDING SERVICES & ENVIRONMENTAL ENGINEER APRIL 2026 Meeting the challenge
Almost all available refrigerants with a GWP below 150 are classified as safety class A2L (low flammability) or A3 (high flammability), according to ISO 817. In environments such as data centres and server rooms, where high availability requirements and strict safety standards apply, any potential flammability hazard, however slight, must be prevented. The solution to this dilemma lies in A2L
refrigerant R454C. Classified under ASHRAE safety standards, A2L refrigerants are non-toxic, flame resistant, highly energy efficient and feature significantly reduced GWP. In fact, as a zeotropic mixture of R1234yf and R32, R454C has a GWP of only 148 and meets the requirements of F-Gas Regulation 2024/573, while at the same time offering a balance between thermodynamic efficiency and safety controllability. When compared to A3 refrigerants, R454C
requires significantly fewer structural and technical protective measures, which facilitates integration into existing systems. In addition, A2L refrigerants can only produce a flammable gas-air mixture at four times the concentration of refrigerant. With a maximum condensation temperature of 65°C, R454C is ideal for the precise climate control of IT infrastructures and can be used in recirculating air conditioning units with a closed refrigeration circuit and an output of up to 50kW until at least 2040.
Safety first
The safe operation of recirculating air conditioning units with R454C requires a holistic safety approach that considers the normative requirements outlined DIN EN 378. Gas detectors with a preset trigger value of 25 per cent lower
explosive limit (LEL) for R454C, in accordance with EN378-3, are required for the early detection of refrigerant leaks. As such, sensors must be installed in locations where refrigerant can accumulate and a level of redundancy is also recommended as an additional safety measure. Monitoring is important and integration into a building management system (BMS) allows centralised supervision and fast intervention if faults occur. When a leak is detected, an automatic safety shutdown immediately deactivates the system and this must include emergency logic that remains operational even during power outages or control system failures. A robust ventilation strategy is also required to ensure refrigerant concentrations in indoor air remain below the lower flammability limit (LFL). This includes forced ventilation with specified air change rates, optimized duct design and automatically triggered emergency ventilation in high-risk areas.
Although R454C offers extensive advantages over other commonly used refrigerants, it does have some technical limitations. Due to its lower volumetric cooling capacity compared to refrigerants such as R410A, slightly larger compressor volumes are required. In addition, both the refrigerant itself and the necessary components and safety systems are currently more expensive than conventional solutions. That said, the production process for these systems is very similar to that for devices with conventional refrigerants, which greatly simplifies production, allowing them to remain cost effective despite the slightly higher material costs.
Sealing the deal
An air conditioning unit using an A2L refrigerant must be permanently sealed. This requires
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