IgG Subclasses Siemens BNTM
BNTM II Latex COMBI kit (Latex IgG3 & IgG4,
Range 0.131-336, sensitivity 0.131 (g/L) IgG2 BNTM
II kit II kit
Range 0.153-98, sensitivity 0.153 (g/L) IgG3 Latex BNTM
II kit
Range 0.003-3.5, sensitivity 0.003 (g/L) IgG4 Latex BNTM
II kit Range 0.0019-2.452, sensitivity 0.0019 (g/L)
It is necessary to open specific channels on the analyser and this may require the assistance of a Siemens engineer. Please enquire for further information.
DESCRIPTION PACK BNTM
(Non-latex IgG1, IgG2, IgG3 & IgG4) IgG1 BNTM
Range 0.066-168, sensitivity 0.066 (g/L) IgG2 BNTM
Range 0.078-50, sensitivity 0.078 (g/L) IgG3 BNTM
Range 0.044-28, sensitivity 0.044 (g/L) IgG4 BNTM
II COMBI kit II kit II kit II kit II kit
Range 0.03-19.2, sensitivity 0.03 (g/L) These non-latex kits are intended for use with BNTM II pre-programmed
parameters. The parameters are provided in the product insert and should be checked against the version of software on the analyser.
DESCRIPTION PACK BN ProSpec® COMBI kit
(Latex IgG3 & IgG4, non-latex IgG1 & IgG2) IgG1 BN ProSpec®
Range 0.131-336, sensitivity 0.131 (g/L) IgG2 BN ProSpec®
kit kit
Range 0.153-98, sensitivity 0.153 (g/L) IgG3 Latex BN ProSpec®
Range 0.003-3.5, sensitivity 0.003 (g/L) IgG4 Latex BN ProSpec®
kit kit
Range 0.0019-2.452, sensitivity 0.0019 (g/L)
It is necessary to open specific channels on the analyser and this may require the assistance of a Siemens engineer. Please enquire for further information.
Small Volume Testing
For laboratories with small numbers of patient samples or if only a small volume of sample is available (e.g. paediatric samples) IgG subclasses may be measured using MININEPHPLUS® 20) or by radial immunodiffusion (RID, page 22).
(page
2x48 test 2x40 test 4x40 test
4x40 test 4x48 test 4x48 test
CODE LK001.P
NK006.P NK007.P LK008.P LK009.P
Siemens BNTM IgA1 BNTM II DESCRIPTION PACK II kit
Range 0.09375-30, sensitivity 0.09375 (g/L) IgA2 Latex BNTM
II kit
Range 0.00315-4, sensitivity 0.00315 (g/L) IgA subclass BNTM
II COMBI kit (Latex IgA2, non-latex IgA1)
A new protocol must be selected in order to run these assays. Beckman IMMAGE®
DESCRIPTION PACK IgA1 Latex IMMAGE®
Range 0.0355-6, sensitivity 0.0355 (g/L) IgA2 Latex IMMAGE®
kit kit
Range 0.005-1.25, sensitivity 0.005 (g/L) Radial Immunodiffusion DESCRIPTION PACK CODE
IgA subclass COMBI -NL RID kit 4 plate kit RK015 2 plates IgA1 range 640-6400** mg/L 2 plates IgA2 range 50-500** mg/L
The ranges quoted are achieved from the assay-specific instrument
protocols. Maximum manufacturing date to expiry is 12 months. *For these assays a validated extended measuring range is achievable by re-running with a manual pre-dilution. Please see package insert for assay-specific manual dilution protocols.
**Diluted sample applied - assay range may be extended using neat sample.
18 More information at:
www.bindingsite.com
40 test 40 test
CODE
LK087.IM LK088.IM
40 test 40 test
2x40 test CODE
NK087.1T LK088.1T LK003.T
4x40 test 4x40 test 4x40 test 4x40 test 4x40 test
CODE
NK001.T NK006.T NK007.T NK008.T NK009.T
non-latex IgG1 & IgG2) 2x40 test IgG1 BNTM
2x48 test 4x40 test 4x40 test 4x48 test
4x48 test
IgA Subclasses II and BN ProSpec® DESCRIPTION PACK CODE LK001.TB
NK006.TB NK007.TB LK008.TB
LK009.TB
IgA subclass concentrations can assist in the investigation of immunodeficiency, autoimmune and infectious diseases. Alterations of the IgA1/IgA2 ratio have been related to specific diseases and to anaphylactic transfusion reactions. IgA2 accounts for only 15% of total IgA therefore a deficiency of IgA2 may not be detected if only total serum IgA concentrations are measured. Grossly elevated levels of either subclass may occur in patients with IgA myeloma.
Latex enhanced reagents are provided for most assays enabling the quantitation of low levels of specific antibody. Each kit contains controls, calibrators and full instructions for running the assay.
Manufacturing date to expiry is maximum 18 months unless otherwise stated. Units in brackets apply to both range and sensitivity.
Binding Site SPAPLUS®
DESCRIPTION PACK IgA SPAPLUS kit*
Range 0.02-28, sensitivity 0.02 (g/L) IgA1 SPAPLUS kit
Range 0.03-6, sensitivity 0.03 (g/L) IgA2 Latex SPAPLUS kit
Range 0.005-1.25, sensitivity 0.005 (g/L) Binding Site Optilite® DESCRIPTION PACK IgA1 Optilite kit
Range 0.035-6, sensitivity 0.035 (g/L) IgA2 Latex Optilite kit
Range 0.005-1.25, sensitivity 0.005 (g/L)
50 test 50 test
CODE
NK087.OPT LK088.OPT
CODE 100 test NK010.S 50 test NK087.S 50 test LK088.S
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