31 Luminescence, UV & Microplate Readers Achieve rapid immunofl uorescent staining in hours


AMSBIO announces the launch of CellO-IF, an innovative all-in-one immunofluorescent staining reagent kit designed to streamline the labelling of organoids and spheroids directly in hydrogels or extracellular matrices. With CellO-IF, you can achieve fast, high-quality staining while preserving delicate structures and cellular integrity.


Immunofluorescence (IF) is a powerful tool for detecting and localising antigens across various tissue and cell types, offering superior sensitivity compared to immunohistochemistry. However, traditional IF staining involves multiple steps and can take several days to complete. CellO-IF revolutionises this by simplifying the process, significantly reducing the time to results from days to mere hours.


By eliminating the need for laborious steps like harvesting, clearing, transferring, and centrifuging, CellO-IF minimises sample loss while maintaining the integrity of the natural 3D structure. This streamlined workflow accelerates research, delivers more reliable results, and enhances the precision of your data.


In addition to its time-saving benefits, CellO-IF offers enhanced antigen visualisation. It consistently produces high-resolution images and is particularly effective in labelling samples that were difficult or impossible to stain using traditional methods.


Available in two optimised formats for labelling both 2D and 3D samples, CellO-IF amplifies target signals, helping researchers achieve clearer, more detailed images and uncover deeper insights from their experiments.


More information online: ilmt.co/PL/LLxR Fluorescent labelling kits for fl ow cytometry and western blots


The new TrailBlazer Tag and TrailBlazer StarBright Dye Label Kits from Bio-Rad Laboratories provide researchers with a streamlined method to conjugate antibodies with high-performance fluorescent dyes for use in flow cytometry and western blotting. These kits offer broad antibody compatibility, exceptional fluorescence stability, and easy integration into multiplex experiments.


The system features two components: a tagging module and a dye labelling kit. Utilising SpyTag and SpyCatcher technology, researchers can efficiently link their antibodies to a selection of TrailBlazer StarBright fluorescent dyes, enabling the creation of customised high-plex panels for flow cytometry and multiplexed fluorescent western blots.


“These kits are designed to provide greater flexibility in experimental design, with multiple fluorescent dye options and seamless antibody labelling,” said Hilary Mavor, Marketing Director, Life Science Group. “With a simple workflow and minimal hands-on time, users can achieve consistent, high-quality conjugated antibodies with superior fluorescence.”


TrailBlazer StarBright Dyes deliver exceptional brightness, narrow excitation and emission profiles, and strong signal stability, ensuring precise resolution of target populations. They are compatible with standard flow cytometers and imaging systems, without requiring special buffers or modifications to existing protocols.


For researchers looking to expand their fluorescence-based experimental capabilities, the TrailBlazer Tag and TrailBlazer StarBright Dye Label Kits offer an accessible and efficient solution for generating custom-labelled antibodies.


More information online: ilmt.co/PL/O3Dj Optimised multi-bandpass fi lters for high-precision fl uorescence imaging


Laser Components offers plasma-deposited hard-coated multi-bandpass filters designed for laser and imaging applications. Available in stock and customisable with up to ten bandpass ranges, these filters enable simultaneous observation of multiple wavelengths using a single optical component - ideal for fluorescence imaging and other advanced applications.


These multi-bandpass filters provide deep blocking between passbands, achieving optical densities greater than OD8, while maintaining over 98% transmission with sharp transition regions. This ensures superior signal clarity and precision in demanding optical systems.


More information online: ilmt.co/PL/LxDD 63870pr@reply-direct.com


63869pr@reply-direct.com 63356pr@reply-direct.com


New fl uorescence detector module


Biotech Fluidics introduces the Mikron 71, the smallest commercially available fluorimeter, designed to elevate fluorescence detection capabilities. With a compact 32 mm diameter and 128 mm length, this high-performance detector is ideal for instruments lacking fluorescence detection, including preparative liquid chromatography systems.


The Mikron 71 features interchangeable, fixed wavelength filters, light sources, and flow cells, allowing for both simulation and emission fluorescence measurements. Powered by a long-life, low-power LED light source, it operates efficiently in chilled environments (down to 4°C/39°F), making it perfect for bioanalytical applications such as protein detection at the nanomolar level.


This versatile detector ensures high accuracy and sensitivity without the need for external calibration, thanks to its integrated reference channel. Connecting via a single USB-C port, the Mikron 71 is easy to set up and compatible with popular chromatography software or can be customised through an open protocol. The device is CE marked and conforms to international standards.


More information online: ilmt.co/PL/9k86 63872pr@reply-direct.com


New Anti-GFP antibodies enhance fl uorescent protein detection


Jackson ImmunoResearch introduces AffiniPure® Rabbit Anti-GFP, expanding its portfolio of secondary antibodies for life science research. GFP is widely used to monitor protein expression and localization within cells. Anti-GFP antibodies enhance detection, enabling researchers to work in conditions where direct GFP fluorescence may be limited.


Affinity-purified and polyclonal, the new Rabbit Anti-GFP antibody detects Aequorea victoria GFP and its variants, including EGFP, ECFP, and EYFP. Available conjugated to Alexa Fluor® dyes and other reporters, it provides strong signal amplification for diverse applications.


Now available in the USA and Europe through Jackson ImmunoResearch and global distribution partners. More information online: ilmt.co/PL/bjl9


63925pr@reply-direct.com


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36