Luminescence, UV & Microplate Readers


Novel nuclear stains for microscopy and fl ow cytometry


Biotium, a leader in fluorescent dyes for life science research, has expanded its NucSpot® Nuclear Stains lineup, providing researchers with unprecedented specificity and flexibility for nuclear counterstaining. NucSpot® Nuclear Stains are membrane- impermeant dyes that selectively target the nucleus with minimal fluorescence until binding to DNA, allowing for convenient no-wash nuclear staining.


This innovative approach distinguishes NucSpot® from traditional nuclear stains, such as propidium iodide (PI), TO-PRO®, and TOTO®, by achieving nuclear specificity in fixed and permeabilised cells without the need for RNase treatment.


Now featuring nine colours across the fluorescence spectrum from green to near-infrared (near-IR), NucSpot® Nuclear Stains offer enhanced flexibility for multicolour panel design, compatible with channels such as FITC, Cy®3, PE, Texas Red®, Cy®5, APC, Cy®5.5, and Cy®7. Many of these stains are non-toxic, suitable for live cell cycle profiling by flow cytometry, and can be used in live cultures for multi-day imaging, providing versatility for a wide range of microscopy and flow cytometry applications.


Dr Lori Roberts, Director of Bioscience at Biotium, remarked: “The expanded NucSpot® lineup offers significant advancements in nuclear counterstaining by broadening colour options and improving photostability over existing cyanine-based stains, without requiring RNase treatment. This expansion reflects our commitment to innovative, user-friendly tools for cell biology research.”


Biotium’s rigorous in-house testing ensures the reliability and consistency of NucSpot® Nuclear Stains, making them ideal for advanced research applications. More information online: ilmt.co/PL/9yz1


63251pr@reply-direct.com High-resolution fl ow cytometer with multi-laser precision


The NovoCyte Opteon spectral flow cytometer from Agilent Technologies offers researchers a powerful and versatile solution for high-precision fluorescence-based cell analysis. Featuring up to five lasers and 73 detectors, this advanced system delivers exceptional resolution and sensitivity, supporting complex multi-parametric experiments.


Designed with a proprietary optics system and cutting-edge electronics, the NovoCyte Opteon ensures superior fluorescence detection and particle size measurement across a wide dynamic range. Integrated temperature control, fluidics monitoring, and real-time sensor circuitry enhance instrument stability and reliability across various experimental conditions.


The latest version of NovoExpress software further streamlines data acquisition, analysis, and reporting, offering an intuitive user experience tailored for efficient and reproducible workflows.


More information online: ilmt.co/PL/bjW5 63871pr@reply-direct.com


Achieving superior instrument precision with fl uorescent calibration standards


Starna Scientific Ltd, with 50 years experience in developing and manufacturing fluorescence reference materials, proudly highlights its enhanced polymer fluorescent references. These advanced materials, featuring proprietary dyes, offer improved calibration accuracy and longevity for fluorimetry systems.


Calibration is crucial for precision in fluorescence-based analytical methods, especially in sectors like life sciences where regulatory compliance is essential. Starna’s innovative references ensure more accurate measurements and instrument control.


These materials are versatile, applicable across fluorometers, point-of-care devices, PCR & diagnostic devices, and microscopy systems. Their robustness ensures traceability and ease of comparison between instruments and measurements, vital for long-term performance.


Starna’s ISO 17034 accreditation guarantees stability and homogeneity, critical for reference material production. In addition, all fluorescent references undergo rigorous individual quality control processes to ensure they meet specific custom requirements. This meticulous attention to detail ensures that these fluorescent references consistently deliver accurate and reliable results for customers. The US Pharmacopeia General Chapter <853> endorses these references for fluorescence instrument qualification.


These references enable precise spectral corrections, essential for inter-instrument comparisons and consistent performance. Available in various formats and concentrations, they ensure optimal performance across different systems.


Starna’s dedication to accuracy and innovation drives the development of these advanced materials, pushing calibration boundaries while maintaining high quality standards. More information online: ilmt.co/PL/QmwD


62667pr@reply-direct.com Compact system for high-sensitivity gel and western blot imaging


The ChemiDoc™ Go Imaging System from Bio-Rad Laboratories is designed for rapid, reliable, and highly sensitive imaging of gels and western blots, all in a compact benchtop format. The ChemiDoc Go Imaging System features advanced CMOS digital imaging technology, capturing gel and western blot images with the same high sensitivity as larger, more expensive instruments. This compact, user-friendly imager supports chemiluminescence and fluorescence detection, including the use of StarBright™ Dyes. Additionally, its three versatile sample trays accommodate a wide range of applications, from nucleic acid to protein quantitation through various detection methods. The system’s all-LED illumination enhances instrument durability and reduces maintenance needs, ensuring consistent and reliable performance over time.


Traditionally, western blot experiments require additional steps for normalisation using housekeeping proteins, which involves time-consuming and costly protocols. The ChemiDoc Go Imaging System offers an alternative with Stain-Free Imaging technology, simplifying the workflow and providing quality control at every stage. The system is also compatible with Bio-Rad’s BR.io cloud-based platform, offering image storage and enhanced data accessibility.


More information online: ilmt.co/PL/7590 63139pr@reply-direct.com


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36