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4 Real-time HPLC monitoring system


FlowChrom by Testa Analytical is an automated, non-invasive system designed to continuously monitor and document HPLC system performance in real time.


While HPLC and UHPLC systems are designed for round-the-clock operation, issues can arise when systems are left unattended, often making it diffi cult to pinpoint the source and timing of problems. Among the most common challenges is solvent delivery system malfunction, highlighting the need for continuous monitoring.


FlowChrom addresses this need by seamlessly integrating with most chromatography data systems (CDS) to provide a digital safety net. It creates a reliable, traceable record of HPLC solvent delivery system performance, fl agging any deviations and confi rming the validity of every separation.


This real-time tracking not only simplifi es troubleshooting but also creates a comprehensive digital archive of HPLC operational data, especially valuable in regulated environments. Additionally, FlowChrom allows scientists and technicians to focus on more productive tasks, reducing the burden of constant monitoring.


More information online: ilmt.co/PL/Lx4d 63707pr@reply-direct.com


PFAS-free degassing for aqueous solutions Biotech Fluidics has introduced the DEGASi®


rates up to 20 ml/min while eliminating contamination from toxic PFAS.


Poly- and perfl uoroalkyl substances (PFAS) are known for their persistence in the environment and links to health issues, including kidney cancer and low birth weights. To address the growing demand from environmental, food, and healthcare laboratories for PFAS-free solutions, this innovative degassing chamber replaces traditional fl uorinated polymer membranes with a silicone-lined fl uid path, ensuring compatibility without PFAS contamination.


By removing dissolved gases, the DEGASi® chamber enhances precision in analytical instruments, reducing bubble formation that can interfere with


dispensing and detection processes. Its design incorporates a highly permeable silicone membrane, with fl uid fl owing through the membrane pathway while a PID-controlled vacuum pump maintains a precise vacuum level to actively extract gases.


This PFAS-free degassing solution supports labs seeking to maintain high analytical performance while aligning with environmentally conscious practices. More information online: ilmt.co/PL/wwDO


63611pr@reply-direct.com New HPLC column oven: Precision temperature control to 90°C


The EchoTherm™ HPLC Column Oven Model CO20 from Torrey Pines Scientifi c is designed to deliver precise temperature control for HPLC columns. With a temperature range from room temperature to 90°C, the CO20 offers exceptional accuracy, adjustable in 0.1°C increments. The oven is equipped with advanced PID control software that maintains temperatures within ±0.1°C, ensuring reliable and consistent results.


The CO20 holds columns up to 30 cm long and accommodates ¼” or 3/8” diameter columns, with space for guard columns and fi ttings. For larger diameter columns, the included column clips can be removed. The oven features easy-to-use controls, a digital display for both target and actual temperatures, an injection counter, and a 30-day timer with alarm and customisable Auto-Off settings. A stable temperature indicator light on the front panel signals when the target temperature is within ±0.2°C.


Operating on 12V DC power, the CO20 includes a universal power supply, 3-wire AC line cord, counter cable, and a 12-month warranty. It is ETL, CSA, and CE compliant, ensuring global compatibility and safety. An optional accessory stand is also available.


More information online: ilmt.co/PL/GM9D 63763pr@reply-direct.com Level up your purifi cation with preparative LC systems


By pioneering High Throughput Purifi cation during the Combinatorial Chemistry era, Gilson has continued the development of state-of-the-art purifi cation platform and software that today support CROs and Biotech Research and Development groups in Synthetic Drugs Discovery such as Peptides or Oligonucleotides Production. Gilson VERITY Preparative LC systems are highly effective in scaling up purifi cation processes from a few milligrams to one gram of compounds using a set of different chromatographic columns, allowing customers to carry out purifi cation of a hundred compounds per year in a reproducible way, a critical step in developing new pharmaceuticals and biotech products. Upgrading an existing VERITY system with mass detection will save a lot of time to researchers by allowing us to identify and immediately collect the desired targeted product with high purity.


If Preparative Chromatography is widely used for the discovery of new active compounds, its ability to isolate compounds with unmatched level of purity at larger scale makes the technology plays a crucial role in the production of high-purity chemicals, pharmaceutical intermediates, and drug candidates to ensure quality, safety, and effi cacy of fi nal products in the chemical and pharmaceutical industries.


The VERITY®


SKID LC is designed to automatically manage all purifi cation steps involved in process scale chromatography such as generates elution mobile phase, injects sample, detects molecules, and collects fractions.


Designed in multiple confi gurations, the VERITY® SKID LC includes advance safety features that make it safe an compliant for pharmaceutical molecule purifi cation non-GMP or cGMP processes.


With over 40 years’ experience in analytical, preparative and industrial scale chromatography. Gilson Purifi cation Services offers custom purifi cation services, helping partners and customers to purify or enrich their molecules of interest. Specialised in complex starting materials, such as biological matrices, natural extracts or fermentations broths, the company offers end-to-end support from feasibility to production through industrial intensifi cation.


More information online: ilmt.co/PL/85lN 63279pr@reply-direct.com T


Life Science Degassing Chamber, offering effi cient removal of dissolved gases from aqueous solutions at fl ow


What’s in the next issue? Find out with a copy of our Media Information Pack.


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