13 Safety, Hazard Containment & Sterilising Equipment
BSC manufacturer considerations and overall conclusions
Although it may be tempting to ask your BSC manufacturer to select your BSC, this approach is likely to fail to meet your organisation’s needs. The manufacturer does not understand all the factors that went into your risk assessment, proposed future work, and the risk tolerance of your organisation. The manufacturer can help with the selection of a model and relevant features that will complement your risk mitigation strategies after your risk assessment is completed.
Conducting a risk assessment for work with biological materials is the critical fi rst step in evaluating laboratory activities and their risks to health and safety. A multi-layered approach of control measures based on NIOSH’s hierarchy of controls should be selected where engineering controls (including BSCs) may be identifi ed as one part of an overall risk reduction strategy.
About the author
Julianne L. Baron is the President of Science and Safety Consulting. She has a background in infectious diseases, biosafety, and public health and consults on laboratory safety and design, pandemic preparedness, and scientifi c communication.
Science and Safety Consulting provides biosafety and biorisk guidance and training to facilitate safe and secure biological research and to prepare organisations for infectious diseases and pandemics. Science and Safety Consulting also facilitates successful scientifi c communication for technical and non-technical audiences.
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References
1. CDC/NIH Biosafety in Microbiological and Biomedical Laboratories (BMBL) 6th Edition:
https://www.cdc.gov/labs/BMBL.html
2. NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines):
https://osp.od.nih.gov/policies/biosafety-and-biosecurity-policy#tab2/
3. WHO Laboratory Biosafety Manual: Risk Assessment monograph:
https://www.who.int/ publications/i/item/9789240011458
4. National Institute for Occupational Safety and Health (NIOSH) Hierarchy of Controls: https://
www.cdc.gov/niosh/topics/hierarchy/default.html
5. WHO Laboratory Biosafety Manual: Biological Safety Cabinets and Other Primary Containment Devices monograph:
https://www.who.int/publications/i/item/9789240011335
6. NSF/ANSI 49-2022 Biosafety Cabinetry: Design, Construction, Performance, and Field Certifi cation Informative Annex I-1:
https://webstore.ansi.org/standards/nsf/ nsfansi492022annex
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