3
Figure 4: Data acquisition frequency comparison between volumetric and Testa thermal fl owmeters. Figure 3: Flow rate of different solvents measured using the Testa fl owmeter.
The faster, higher resolution data acquisition offered by the Testa Analytical thermal fl owmeter not only can improve data quality but can also offer considerable saving of precious labour time in particular at low fl ow rates, where volumetric fl owmeters are slow to generate a single datapoint.
In addition, using this new generation of digital thermal fl owmeters, it is possible to interface them directly with chromatography data system allowing storage of fl ow data along with each chromatogram from your liquid chromatography system. This technological advance opens a whole new chapter to the concept of total quality assurance, as each chromatogram may now be evaluated under the light of the fl ow rate delivered by the pump during that one chromatogram.
Conclusion
Historically volumetric fl owmeters have been the technique of choice when the performance of a liquid chromatography pump needed to be validated or qualifi ed for a particular application. Their performance with aqueous separations at room temperature has made them a tried and trusted method. However, technological advances in real-time non-invasive thermal fl owmeter design now make it possible to not only match the performance of any volumetric fl owmeter, but also offer a range of exciting new benefi ts to the user. These new capabilities include wide-ranging solvent compatibility, greater fl exibility and, probably most important of all, a reduction in the time required for the validation or qualifi cation task. Compact and lightweight in design, these thermal fl owmeters are powered and transmit measured fl ow data in real time via an integral USB interface. A PC based app allows continuous recording and storage of the measured fl ow rates.
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www.labmate-online.com Solvent recycler drives sustainability in pharma labs
Biotech Fluidics has announced that a leading pharmaceutical company has invested in 17 SPR-200 solvent recycler units to enhance the sustainable use of solvents in HPLC systems across its analytical laboratories.
The SPR-200 operates as a standalone, externally powered unit, eliminating the need for an external computer and avoiding potential connectivity challenges with IT systems.
Designed for compatibility with most HPLC systems, the SPR-200 continuously monitors detector output signals during liquid chromatography. In customer laboratories, it has demonstrated the ability to recover up to 90% of the mobile phase by redirecting purifi ed solvent into a dedicated reservoir during isocratic HPLC.
Fritiof Ponten, CEO of Biotech Fluidics, commented: “Controlled via an integral LED screen and membrane keyboard – the SPR-200’s user- friendly software allows you to confi gure operational parameters and to perform online monitoring and create an audit trail of recovered solvent.”
He added: “Not only does the SPR-200 improve sustainability in your lab, but it also quickly pays for itself by enabling you to recycle nearly all the solvent used in your isocratic HPLC systems.”
More information online:
ilmt.co/PL/1yBN 63687pr@reply-direct.com
Revolutionising HPLC: New LC Series offers advanced automation and sustainability
Agilent Technologies has unveiled its next-generation Agilent Infi nityLab LC Series, comprising the 1290 Infi nity III LC, 1260 Infi nity III Prime LC, and 1260 Infi nity III LC systems, including biocompatible options. These systems are the fi rst to feature the new Agilent Infi nityLab Assist Technology, designed to streamline lab operations with advanced automation and system assistance.
The Infi nityLab Assist helps optimise tasks by automating instrument routines, simplifying sample preparation, and assisting with maintenance and troubleshooting. The inclusion of barcoding and camera technologies enhances sample tracking and reduces the likelihood of errors, improving accuracy and effi ciency.
With this launch, Agilent aims to improve lab productivity by minimising manual operations and reducing operator training time. Infi nityLab Assist technology provides real-time insights into system health, assisting analysts at all levels in achieving faster, more reliable results.
The new systems are also compatible with previous LC models and integrate seamlessly with chromatography data systems (CDS). Verifi ed by the ACT 2.0 Ecolabel, these systems prioritise sustainability, being the fi rst LC systems to provide users with a CO2
footprint analysis.
Philip Binns, President of Agilent’s Life Sciences and Applied Markets group, highlighted that this new series sets a benchmark in liquid chromatography, offering a robust solution for labs looking for enhanced automation, precision, and sustainability.
The Infi nity III LC Series was launched globally in October 2024 at major scientifi c events including HPLC 2024 in China, PharmSci 360 in the US, and the HUPO World Congress in Germany.
More information online:
ilmt.co/PL/85qo 63485pr@reply-direct.com
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