Laboratory Products 51 Flowchem Firm’s Technology Passes 1000 Publication Citations Milestone


Vapourtec has recently passed the signifi cant milestone of its technology being cited within 1000 peer reviewed scientifi c publications,, cementing its position as a world leader in the design and manufacture of laboratory scale fl ow chemistry systems.


Founded in 2003 and based near Cambridge, UK, Vapourtec’s systems have contributed towards the development of exciting new synthetic routes for important therapeutics including breast cancer drug Tamoxifen, Artemisinin for the treatment of malaria and peptide drugs focused on the treatment of type 2 diabetes.


The 1000th citation covered the α-alkylation of ketones in fl ow and was published by McGlacken group at University College Cork.


Chief Scientifi c Offi cer Dr Manuel Nuño explained: “This is a remarkable milestone and is due to the talent and dedication of our customers and collaborators whose breakthroughs have enabled progress in many fi elds of chemistry research including photochemistry, electrochemistry, polymerisation and peptide synthesis. “It places us way ahead of the competition in terms of the number of publication citations and is evidence of the rapidly growing impact and profi le of fl ow chemistry. “We have come a long way since our fi rst publication citation in 2006. That was published by the Ley group and covered automated continuous fl ow synthesis of 4,5-disubstituted oxazoles with the latest publication covering Continuous Flow-Facilitated CB2 Agonist Synthesis published by the Kappe group.


“Our mission is to empower and enable scientifi c discovery through the provision of innovative and precise technology to chemists within industry and academia.


“Many active pharmaceutical ingredients, originally synthesised using a batch approach, can be produced far more effi ciently under continuous process conditions bringing down real world costs for the treatment of a myriad conditions,” added Manuel. Vapourtec has provided over 750 R-Series and E-Series fl ow chemistry systems to laboratories in 23 nations around the world. Manuel concluded: “We never stand still, are always innovating in the name of science and look forward to enabling many more revolutionary breakthroughs in the future.” More information online: ilmt.co/PL/16VW


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Innovative pH Measurement Method for Particle Sizing


New Desiccant with Colour-Changing Indicator


Elemental Microanalysis, a leading global supplier to the elemental analysis market, is pleased to announce brand new drying agent, DrysorberTM indicators.


(B1327) with colour changing


Elemental’s in-house R&D team developed every aspect of Drysorber to be easy to use – from tube fi ll to moisture indication. Drysorber is composed of several sizes of drying agent spheres and an indicator. The larger spheres of drying agent will dissolve as they are spent. Elemental’s Drysorber also contains an indicator which will undergo a change from pale blue to pink as the larger spheres absorb water. The colour indicator offers easy recognition of when the drying agent needs replacing - as well as confi rmation that any opened, stored product is still viable for use.


Fritsch has pioneered a ground-breaking method to measure the pH value of dispersion liquids directly within the measuring unit. The newly integrated pH sensor module in the dispersion bath is connected to the Laser Particle Sizer, enabling continuous pH monitoring during measurements and automatic data transfer to the software for documentation.


This patented approach proves signifi cantly more effective in handling fl uctuations compared to the zeta potential method. It offers substantial advantages, particularly in research and development contexts. The pH value holds broader signifi cance, especially in nano-suspension measurements, providing valuable insights into how chemically inert materials react to varying environmental conditions. When measurement curves are unstable, the pH value aids in stabilisation and interpretation. Moreover, Fritsch’s newly introduced patented pH measurement method allows for precise observation, facilitating the detection of agglomeration or aggregation.


FRITSCH Particle Sizers offer state-of-the-art particle sizing solutions, catering to both production and quality control, as well as research and development applications, and manufacturing process control. The Fritsch A-22 NeXT Nano, a Laser Particle Sizer, excels in accuracy and sensitivity, covering a wide measuring range from 0.01 to 3800 μm. Additionally, a Micro version offers an economical alternative with a measuring range from 0.5 to 1500 μm. Both models feature a single laser and numerous patented features to ensure maximum durability and minimal maintenance.


These instruments are designed for easy installation through plug-and-play functionality, tool-free cleaning with simple steps, and come with high-performance software, meeting 21 CFR Part 11 requirements. Fritsch Laser Particle Sizers ANALYSETTE 22 NeXT adhere to a smart, modular concept, allowing customers to purchase only the necessary components and scale their sizing capabilities as needed.


Contact Fritsch for videos, whitepapers, sizing protocols, and other resources on laser particle sizing.


More information online: ilmt.co/PL/VeG3 and ilmt.co/PL/8Nev


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“The obsolescence of Sicapent to the elemental analysis market offered an opportunity for Elemental Microanalysis to develop a drying agent in-house for the needs of our customers with Elementar analysers,” noted Paul Stevens, Director of Operations. “Our R&D team, helmed by David Castle, developed a desiccant that is both uniquely non-clumping and offers distinct visual clue on replacement status.”


Drysorber is suitable for use in Elementar® analysers where Sicapent® was previously recommended, in instrument modes for C, H, N, and


O detection. Supplied in a 230 g bottle, this granular, free-fl owing product ensures easy fi lling of drying tubes. Additionally, Drysorber is not considered dangerous goods for shipping at the 230g size.


More information online: ilmt.co/PL/X1w8 61258pr@reply-direct.com


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