Laboratory Products 23 Programme details for the 11th Confocal Raman Imaging Symposium Announced


The 11th Confocal Raman Imaging Symposium will be held from 29th September to 1st October in Ulm, Germany. The well-established, annual symposium will cover various aspects of modern Raman microscopy and will provide deep insights into Confocal Raman Imaging and its applications. Over the past several years the symposium has become increasingly important for the Raman community, helping participants to keep up with the latest developments in modern Raman imaging and to share their knowledge with one another.


After the great success of last year’s symposium the organising committee has again assembled a diverse and interesting program which will meet the highest demands of the attendees. This year’s invited speakers are distinguished experts in the field of Raman spectroscopy from academia and industry. Their talks will highlight a broad range of Raman spectroscopy applications in life science, nanotechnology, materials science, graphene research, and climate research. The program also includes a talk of Prof. Albert Zink from the EURAC-Institute for Mummies and the Iceman about Raman investigations of the Tyrolean Iceman. In addition, technical talks about the general principles, microscope configurations and resolutions will give the participants a deeper understanding of confocal Raman microscopy.


Further conference highlights are the contributed talks and posters session, to which all attendees are invited to submit their abstracts, the conference dinner with the best poster award ceremony and the demonstration of the new RISE Microscope for correlative Raman Imaging and Scanning Electron Microscopy.


This three-day symposium is an excellent occasion for scientists and engineers to further their knowledge of this highly valuable technique in order to meet emerging requirements in the chemical identification and imaging of various compounds. Typical research fields for confocal Raman imaging include pharmaceutics and cosmetics, materials and polymer sciences, nanotechnology, medical and life science, archaeology and geology, forensics, coatings, thin-films and all fields in which clear identification of the distribution of chemical compounds is a necessity.


For more details, program and registration information please go to www.raman.net 31133pr@reply-direct.com


Water Activity Analyser meets the needs of Pharmaceutical Industry


Labcell Ltd, the exclusive UK distributor for Decagon Devices, is promoting the AquaLab Series 4TE water activity analyser as an accurate, quick, simple and cost-effective way in which pharmaceutical companies can gain valuable information about gels, powders, pastes and tablets. The AquaLab Series 4TE makes accurate measurements of the water activity in active ingredients, excipients and formulations. Water activity measurements are increasingly being viewed as essential when following due course and process as part of GMP because water activity has a significant bearing on product stability, as well as the handleability of materials in production and packaging equipment.


The AquaLab Series 4TE enables lab-quality measurements of water activity to be made almost anywhere in the production environment. It is equally suitable for use by formulation and research and development teams, as well as those working on new packaging designs.


A notable feature of the AquaLab Series 4TE is temperature equilibration, meaning that users can set the sample temperature to anything from 15 to 50oC; the analyser then maintains that temperature throughout the test. Measurements are obtained in five minutes or less. The instrument has a measurement range of 0.030 to 1.000 aw, an accuracy of +/-0.003 aw and a repeatability of +/-0.001 aw.


Users in the pharmaceutical industry will appreciate the way in which the AquaLab Series 4TE handles data with a strong emphasis on traceability. Data is captured on the instrument and cannot easily be deleted; it can also be downloaded to a computer for archiving and more detailed analysis. Up to 8,000 data points can be stored securely on the AquaLab and the date, time and operator is logged for every measurement and calibration. Each instrument comes with a licence for Decagon’s own PC software, with the instrument and software both complying with the requirements of the FDA’s 21 CFR Part 11 rule regarding electronic records and signatures.


Labcell also supplies the AquaLab Series 4TEV which is identical to the Series 4TE in most respects yet benefits from an additional hygroscopic polymer capacitance sensor for analysing samples containing volatiles. Users can switch between this sensor and the standard dewpoint sensor via the instrument’s front panel menu. Accuracy with the volatiles sensor is +/-0.015 aw.


31127pr@reply-direct.com Make a Big Impression on Ultra Small Batch Production


The new series of Picoline machines, developed for ultra small batch production of one to hundreds of grams of material, offers the widest wet and dry processing options for clinical trials or ultra small scale production available on the market. Meeting the demands of R&D departments, research institutes and those processing expensive materials and active pharmaceutical ingredients this unique equipment for size reduction, mixing, classifying and particle design is developed in miniature from existing and proven Hosokawa Micron technology.


The Picoline range comprises of nine individual machines which can all be fitted into the same compact operating housing. The range includes Picoplex based on the UPZ impact mill, Picozirk an impact classifier mill, Picosplit which is an ultrafine air classifier, Picojet based upon the well know AFG opposed jet mill with integral classifier for ultrafine grinding, Piconizer a spiral jet mill, based on the Alpine AS mill, Picocross a pin mill, Picoliq a wet agitated media mill, largely identical to the AHM mill, Picobond a high energy mixer largely identical to the Nobilta product line and Picomix a high performance batch mixer for dry powders. The flexibility of single housing and easily transposable machines is a major plus point.


Developed from established Hosokawa machines, transfer to volume production is straight forward, reliable and problem free enabling a swift route to market for new products under development. Suitable for bench top or housing in a fume cupboard or compact isolator the units are easy to clean and user friendly. Controlled by means of a touch


panel with a microprocessor housed within the platform operating data, settings and system flowcharts etc can be displayed and transmitted to external printers, USB sticks or LMS systems. A range of accessories for feeding, metering etc is also available.


30657pr@reply-direct.com


Temperature Controlled Stage used to Study Metal-Organic Frameworks Using Second Harmonic Generation Microscopy


Linkam Scientific Instruments report on the use of their THMS600 temperature controlled stage in the study of metal-organic frameworks using Second Harmonic Generation Microscopy at the University of Leuven. With the advancement of technology and the demand for more in-depth information, newer microscopy techniques such as Second Harmonic Generation (SHG) Microscopy are being used by scientists worldwide to further their research.


Dr Karen Markey from the University of Leuven, Belgium, is one such researcher who is reaping the benefits of these advancements by using SHG Microscopy to investigate the structure of materials in a manner that cannot be achieved through other, more conventional microscopy techniques.


Dr Markey and her colleagues in the university’s molecular electronics and photonics department have been using and fine tuning an SHG technique developed by Assistant Professor Monique van der Veen from the Technical University of Delft that can allow them to study the structure of metal-organic frameworks (MOFs). As part of this set-up, they have generally been using a wide field microscope and, more recently, a laser scanning microscope with an intense frequency of 800 nm. The team take several images of the same sample, but use different polarisations of the laser light. Plotting the variation of SHG intensity as a function of the polarisation gives an insight into the crystal structure of the samples. With such small variations in optical density being of such importance, the control of the environmental conditions in which the sample is being held becomes even more vital. This was possible using a Linkam THMS600 stage.


Dr Markey was particularly impressed by the variety of parameters that can be controlled by the stages, she said: ”You can easily set the desired temperature programs and also measure under N2 flow, which is important for the materials we work with. It is an ‘all in one’ solution.”


To see the full paper on this application please visit: www.linkam.co.uk/application-notes. 30396pr@reply-direct.com


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