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17


Immobilised Chiral Columns Pave theWay to Novel Separations


High-speed analysis and reproducible results are paramount to efficient pharmaceutical research and development. CHIRALPAK®


IA,


IB and IC immobilised polysaccharide columns fromChiral Technologies allow chemists to choose froma large assortment of organic solvents. Use of CHIRALPAK immobilised


Superior TLC Scanning from CAMAG


columns helps to develop new separations and attain high levels of enantioselective recognition of chiralmolecules. The choice ofmobile phase content in both enantioselective high-performance liquid chromatography (HPLC) and supercritical fluid chromatography (SFC) has expanded dramatically to a greater variety of organic solvents due to the stability of the immobilised polysaccharide phases. By using practically any organic solvent in conjunction with three immobilised chiral stationary phases (CSPs) - CHIRALPAK IA, IB or IC - chemists canmaximise success rates in compound screening for identifying an effective separation of chiralmolecules by


enantioselective HPLC and SFC. Additionally, immobilised column selectivities are complementary to those of coated polysaccharide-based CSPs, leading to a high degree of success in screening for a successful separationmethod using the available coated phases in a combination with CHIRALPAK IA, IB and IC. The immobilised columns have been successfully employed in pharmaceutical research and development applications. The advent of CHIRALPAK IA, IB and IC offers enhanced compound solubility, greater column stability and novel column selectivity, all of which improve column lifetime.


Formore information visit www.chiraltech.com Compound Purification


with Confidence New Flash/LC Purification Solution from Varian, Inc.


Omicron Research Limited, CAMAG’s UK distributor, is proud to announce the new CAMAG TLC Scanner – successor to the TLC Scanner 3 – which was unveiled at Analytica 2010 in Munich and attracted wide interest amongst the visitors there. The CAMAG TLC Scanner is the most advanced workstation for the densitometric evaluation of Thin-Layer chromatograms currently available. Analysts can now use the entire spectral range from 190 to 900 nm with high spectral selectivity for data acquisition.


Key features of the new CAMAG TLC Scanner include measurement of objects up to 200 x 200 mm. Within minutes up to 36 tracks and up to 100 substances per track can be analysed. The unit has a compact footprint and an improved plate loading and handling system for user convenience. Easy to use winCATS software enables reporting with analytical results automatically calculated, providing statistical data including the complete set of parameters used from scanning raw data to documentation in one single file. The CAMAG TLC Scanner is GMP/GLP and 21CRF11 compliant. Further information on the CAMAG TLC Scanner 3 is available from Omicron on info@omicron-uk.com


Innovative and Easy: Six Clicks to Compound Purification


Varian’s Flash/LC Purification System allows you to focus on compound synthesis and spend less time purifying. Only six clicks from crude sample to purified compound.


wizard esis


971-FP System


IntelliFlash™ Software SuperFlash™ Columns


DASi™ Sample Injection Module Technical Support


• Intuitive “Guide Me” wiizard identifies the correct purification method for each compound, for full confidence in your target compound


purification


• “Sample Safe” features: your sample is never invisible and sent to waste, saving re-synthesis time


r full confidence in your target compound s:


invisible re-synthe


• “Ready to Run” technology ensures the system is ready for faster compound purification


y technollogy gy urification


Request a copy of our new Flash Solutions brochure and data sheets - email flashpur@varianinc.com (quoting ‘Flash 1’)


Learn more about Varian’’s purification solutions at: www.varianinc.com


s purification solutions


Chromatography • Spectroscopy • Mass Spectrometry • Magnetic Resonance Spectroscopy and Imaging • X-Ray Crystallography • Dissolution • Consumables • Data Systems • V


ometry • Magnetic Resonance Spectroscopy and • Consumables • Data Systems • Vacuum


ash Solutions brochure and data aninc.com (quoting ‘Flash 1’)


y ready dy when y you are, t compound


© 2010 Varian, Inc.


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