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RESEARCH ROUND-UP |


research round-up


BODY SHAPING WITH ACOUSTIC WAVE THERAPY AWT®/EPAT®: RANDOMIZED, CONTROLLED STUDY ON 14 SUBJECTS


Adatto MA, Adatto-Neilson R, Novak P, Krotz A, Haller G. J Cosmet Laser Ther 2011; 13(6): 291–6


very frequent request among the female and male population. Objective: The objective of this study is to demonstrate the efficacy and safety of AWT®, combining two different mechanical waves, planar AWT and radial AWT during the same session, in volume reduction of saddle bags in women. Methods: Treatment was performed on the saddle bag areas of 14 female patients, with the CELLACTOR® SC1 (Storz Medical AG,


R EDUCTION OF LOCALISED adiposities by non invasive means is a


Tägerwilen, Switzerland) using extracorporeal pulse activation technology, EPAT®. This device includes two handpieces, the C-ACTOR® and the D-ACTOR®. Within 4 weeks, eight AWT® treatment sessions have been performed with both applicators. Follow-up visits were performed 1, 4 and 12 weeks after the last treatment. Results: Measurements with the ultrasound system clearly demonstrate a significant diminution in the subcutaneous fat layer thickness and a reduction of the averaged circumference of thighs. Conclusions: This study, although performed on a small number of patients, tends to show the safety and efficacy of AWT® in treating localized fat areas in a non-invasive way. There is also an additional benefit for patients in reducing the cellulite appearance and improving the skin firmness at the same time by using AWT®.


in the Caucasian population and its incidence is increasing worldwide. Although surgical procedures show a high cure rate with acceptable morbidity, non-surgical, pharmacotherapeutic approaches have been regarded as appropriate alternatives, and/or first-line treatments, in selected cases. Imiquimod (IQ) is a synthetic imidazoquinoline amine that locally enhances, through cytokine induction, both innate and acquired immune pathways, resulting in immunomodulating, antiviral and antitumor effects. Topical IQ 5% cream is approved by the FDA and the European Union for the treatment of small superficial BCCs (<2.0 cm); however, published data highlight the possibility of successful outcomes in larger lesions. We report three patients, each one presenting with a large BCC and successfully treated with IQ 5% cream. Although our cases and those from the literature do not rise to the level of evidence, IQ may be a reliable, efficacious and safe non- surgical option for selected cases of large superficial BCCs. Histological examination should occur at baseline and at the end of treatment along with clinical and dermatoscopic examination at least monthly during the course of the treatment and every 6 months for 2 years following the treatment.


B 68 ❚ January/February 2012 | prime-journal.com


A round-up of the most recently published academic articles and research


SUCCESSFUL TREATMENT AND MANAGEMENT OF LARGE SUPERFICIAL BASAL CELL CARCINOMAS WITH TOPICAL IMIQUIMOD 5% CREAM: A CASE SERIES AND REVIEW


Lacarrubba F, Potenza MC, Gurgone S, Micali G. J Dermatolog Treat 2011; 22(6): 353–8


ASAL CELL CARCINOMA (BCC) IS THE most common non-melanoma skin cancer


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