PEER-REVIEW | SKIN REJUVENATION | VoluDerm is a safe and effective microneedle technology
for dermal volumizing and the treatment of wrinkles with minimal pain and no downtime22
.
Clinical experience with Hybrid Energy According to the author’s clinical experience, HE provides a fractional cold denaturation of dermal protein, through alkalizing and tissue apoptosis. HE microneedling creates micro-column punctures. These columns of mechanical punctures are not bordered by thermal coagulation tissue and allow infusion of the mesolift product to increase the efficacy of the procedure and protein synthesis. In the author’s clinic, HE technology is commonly
combined with the application of various substances such as hyaluronic acid (Figure 1). When comparing the effect of the infusion methods of other products, such as mesotherapy treatments, the infusion was found to be more effective using the HE technology, which was shown to have less downtime, fewer side effects, and a smaller pain level. With the HE technology the ablation zones remain vital, and the stimulation of the healing process due to the emitted energies may facilitate absorption of applied substances. In addition, the healing process following mesotherapy may be longer with a greater risk of infection as the needles used are normally thicker. Unlike other technologies, the author
is able to treat areas that are prone to side effects or contraindicated with other technologies, such as the tear trough area (Figure 2), the thorax, and glands in the neck allowing full neck tightening (Figure 3) and skin renewal, as well as smoker’s lines and lip volumizing in a natural, substance free manner. Expected results of the HE treatments are significant dermal refilling, and a reduction of wrinkles including nasolabial wrinkles and perioral and periorbital lines. Skin texture improvement presented as radiant skin, smaller pores and dermal volume increase can also be expected. Post treatment, slight erythema and edema will
appeared immediately, and will disappear within a few hours (Figure 4). A subtle tiny crust matrix pattern occasionally appeared 1 to 2 days post treatment (Figure 5). No undesired side effects were experienced by any of
the patients, they all described the treatment as comfortable and in most cases the author did not use any numbing cream. Three to five treatments were usually performed, spaced 1–2 weeks apart.
Conclusion The new novel Hybrid Energy™ Technology delivers thermal and electrical energies to create controlled micro ablation zones penetrating to the mid-dermis. HE treatments promote a natural fractional healing process
44
Figure 5 (A) Ex-vivo UV aged skin histology samples at D0 and (B) D2 in survival medium. (H&E stain, magnification: x200 Left, x100 Right). (A) immediately after treatment with HE at low level. Micro-ablation effect is visible into upper dermal layer. (B) After 2 days in survival medium. Healing process including collagen regeneration and epithelialization is demonstrated
for dermal volume refilling and skin renewal. The author performed HE treatments that demonstrated skin refilling effect along with improvement of skin texture and irregularities. No significant adverse effects were detected and treatments were well tolerated by patients with minimal to no pain and no downtime.
Declaration of interest None Figures 1–5 © Dr Beilin
Key points Hybrid Energy
combines thermal and non-thermal controlled ablation zones to trigger the wound healing process
The Hybrid Energy
treatment has minimum to no pain bleeding or downtime
The column channels
created by the micro- needles are receptive for the active infusion of materials
Dr Beilin’s clinical
experience has demonstrated long lasting results that improve with time
Areas that are
traditionally banned from being treated with injectables and other fractional technologies are now easily treated and improved with the Hybrid Energy technology
References
1. Gold MH. Tissue tightening: a hot topic utilizing deep dermal heating. J Drugs Dermatol 2007; 6: 1238–42
2. Alster TS, Lupton JR. Nonablative cutaneous remodeling using radiofrequency devices. Clin Dermatol 2007; 25: 487–91
3. Sadick N, Sorhaindo L. The radiofrequency frontier: a review of radiofrequency and combined radiofrequency pulsed light technology in aesthetic medicine. Facial Plast Surg 2005; 21: 131–8
4. Goldman P, Fitzpatrick E. Cutaneous Laser Surgery — the art and science of selective photothermolysis. Mosby, 1999. p377
5. Kaplan H, Gat A. Clinical and histopathological results following TriPollar radiofrequency skin treatments. J Cosmet Laser Ther 2009; 11(2): 78–84
6. Boisnic S, Branchet MC. Ex vivo human skin evaluation of localized fat reduction and anti-aging effect by TriPollar radio frequency treatments. J Cosmet Laser Ther 2010; 12(1): 25–31
7. Levenberg A. Clinical experience with a TriPollar radiofrequency system for facial and body aesthetic treatments. Eur J Dermatol 2010; 20 (5): 615–9
8. Shapiro SD, Eros Y, Abrahami Y, Leviav A. Evaluation of safety and efficacy of the
TriPollar technology for treatment of wrinkles Publication. Las Surg Med 2012; 44(6): 453–8
9. Spadoni D, Cain CL. Facial resurfacing. Using the carbon dioxide laser. AORN J 1989; 50: 1007, 1009–1013
10. Weinstein C. Ultrapulse carbon dioxide laser removal of periocular wrinkles in association with laser blepharoplasty. J Clin Laser Med Surg 1994; 12: 205–209
11. Waldorf HA, Kauvar AN, Geronemus RG. Skin resurfacing of fine to deep rhytides using a char-free carbon dioxide laser in 47 patients. Dermatol Surg 1995; 21: 940–946
12. Teikemeier G, Goldberg DJ. Skin resurfacing with the erbium:YAG laser. Dermatol Surg 1997; 23: 685–687
13. Manstein D, Herron GS, Sink RK, et al. Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury. Lasers Surg Med 2004; 34: 426–438
14. Laubach HJ, Tannous Z, Anderson RR, Manstein D. Skin responses to fractional photothermolysis. Lasers Surg Med 2006; 38: 142–149
15. Tierney EP, Eisen RF, Hanke CW. Fractionated CO2 laser skin rejuvenation. Dermatol Ther 2011; 24(1): 41–53
16. Hantash BM, Ubeid AA, Chang H, Kafi R, Renton B. Bipolar fractional radiofrequency treatment induces neoelastogenesis and
neocollagenesis. Lasers Surg Med 2009; 41(1): 1–9
17. Hantash BM, Renton B, Berkowitz RL, Stridde BC, Newman J. Pilot clinical study of a novel minimally invasive bipolar microneedle radiofrequency device. 2009; 41(2): 87–95
Lasers Surg Med
18. Alexiades-Armenakas M, Rosenberg D, Renton B, Dover J, Arndt K. Blinded, randomized, quantitative grading comparison of minimally invasive, fractional radiofrequency and surgical face-lift to treat skin laxity. Arch Dermatol 2010; 146(4): 396–405
19. Park J, et al. The use of microneedle fractional radiofrequency system in wrinkle reduction and skin tightening. White paper, Dept. of Dermatology, Yonsei Univ. College of Medicine, Seoul, Korea.
20. Boisnic S, Branchet MC. Ex vivo study of hybrid energy technology using a human skin model. Eur J Dermatol 2014; 24(1): 46–52
21. Gershonowitz A, Gat A. VoluDerm Microneedle Technology for Skin Treatments — In Vivo Histological Evidence. J Cosmet Laser Ther 2015; 17(1): 9–14
22. Shapiro SD. Voluderm Micro-Needle Technology for Treating Skin Laxity and Wrinkles-Initial Clinical Experience. J J Exper Derm, 2015; 1(1): 006
August/September 2015 |
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